Results 31 to 40 of about 19,313 (263)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Faire théorie pour faire science ?
The paper questions how theoretical production has been conceived as a way to scientize French literary studies in the 1960s and 1970s. The emergence of structural methods engaged reflections on scientificity in the Humanities, which were extended in the
Lucile Dumont
doaj +1 more source
Vers une histoire de l’art engagée ?
The article examines new theoretical and methodological approaches in the humanities, particularly in art research, advanced recently by Anglo-Saxon researchers.
Ewelina Chwiejda
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Knowledge exchange and the creative industries: A reflective commentary on current practice
This reflective commentary summarizes the key learnings that arose from the 2019/20 Knowledge Exchange and the Creative Industries seminar series. These seminars at the University of Bristol, UK, looked at engagement with research within the creative ...
doaj +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Double-Valued Neutrosophic Offset for Enhancing Humanistic Competence: An Effectiveness Study of Humanities Instruction in Vocational College Students [PDF]
In the context of increasingly skills-oriented education, vocational colleges face the challenge of producing technically competent graduates who are also ethically grounded, culturally aware, and socially responsible.
Lingling Lin
doaj +1 more source
This essay cluster features two essays by students and faculty collaborators describing the ways in which new forms of pedagogical practices are expanding and changing the field of Digital Humanities.
Arun Jacob +4 more
doaj +2 more sources

