Results 121 to 130 of about 3,928,365 (313)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Measuring person-centred care in the mission, vision, and core value statements of Canadian healthcare organizations

BMC Health Services Research
Background Person-centred care (PCC) has been shown to improve health outcomes. The inclusion and incorporation of person-centredness in care has been a growing priority for healthcare organizations across Canada.
Iqmat Iyiola, Sadia Ahmed, Paul Fairie, Matthew Luzentales-Simpson, Kimberly Manalili, Maria J. Santana   +5 more
doaj   +1 more source

Employee engagement and its importance to HPWPs (High Performance Work Practices), employee outcome relationship in the Nigerian hotel sector [PDF]

, 2020
KU Odiaka
openalex  

Replication Data for: The Impact of Professional Training in Public and Policy Engagement

, 2023
Kathryn Urban
openalex   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Rethinking the Value of Education amid the Economic Crisis: The Experiences of University Graduates

Education Sciences
Even though many nations invest heavily in education to boost economic growth and development, evidence continues to show that university graduates struggle to find employment and eke out a living, obscuring our understanding of the true value of ...
Pfuurai Chimbunde, Byron Brown
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The Relationship Between the Civic Engagement of Parents and Children

, 2016
Mario Quaranta, Giulia Maria Dotti Sani
openalex   +2 more sources

Strategy for Engagement with Foundations [PDF]

, 2012
The strategy for engagement with philanthropic foundations was adopted by UNDP senior management in July 2012. This strategy aims to reposition and strengthen UNDP's work with foundations vis a vis the new developments in the philanthropic sector and ...

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