Results 1 to 10 of about 47,402 (142)

Enabling genome editing in tropical maize lines through an improved, morphogenic regulator-assisted transformation protocol [PDF]

Frontiers in Genome Editing, 2023
The recalcitrance exhibited by many maize (Zea mays) genotypes to traditional genetic transformation protocols poses a significant challenge to the large-scale application of genome editing (GE) in this major crop species.
José Hernandes-Lopes, José Hernandes-Lopes, Maísa Siqueira Pinto, Maísa Siqueira Pinto, Letícia Rios Vieira, Letícia Rios Vieira, Patrícia Brant Monteiro, Patrícia Brant Monteiro, Sophia V. Gerasimova, Sophia V. Gerasimova, Sophia V. Gerasimova, Juliana Vieira Almeida Nonato, Juliana Vieira Almeida Nonato, Maria Helena Faustinoni Bruno, Maria Helena Faustinoni Bruno, Alexander Vikhorev, Fernanda Rausch-Fernandes, Fernanda Rausch-Fernandes, Fernanda Rausch-Fernandes, Isabel R. Gerhardt, Isabel R. Gerhardt, Isabel R. Gerhardt, Laurens Pauwels, Laurens Pauwels, Paulo Arruda, Paulo Arruda, Paulo Arruda, Ricardo A. Dante, Ricardo A. Dante, Ricardo A. Dante, Juliana Erika de Carvalho Teixeira Yassitepe, Juliana Erika de Carvalho Teixeira Yassitepe, Juliana Erika de Carvalho Teixeira Yassitepe   +32 more
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Lysine α-ketoglutarate reductase as a therapeutic target for saccharopine pathway related diseases [PDF]

Frontiers in Molecular Neuroscience
The saccharopine pathway (SacPath) and the pipecolate pathway (PipPath) catabolize lysine to α-aminoadipate. Although the PipPath has been highlighted as the prominent route operating in the brain, recent work has demonstrated that the SacPath plays a ...
Gabriel Vieira Valderrama, Gabriel Vieira Valderrama, Gabriela Alves Moreira, Gabriela Alves Moreira, Paulo Arruda, Paulo Arruda, Paulo Arruda   +6 more
doaj   +2 more sources

Identification of electron transfer enzymes in Thermoanaerobacterium saccharolyticum [PDF]

Journal of Bacteriology
Thermoanaerobacterium saccharolyticum is a promising candidate for the production of biofuels from lignocellulosic sugars; however, the genes associated with electron transfer from ferredoxin are poorly characterized. In this work, we deleted several key
João H. T. M. Fabri, Layse C. de Souza, Luana W. Bergamo, Lee R. Lynd, Daniel G. Olson   +4 more
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Genetic investigation of hydrogenases in Thermoanaerobacterium thermosaccharolyticum suggests that redox balance via hydrogen cycling enables high ethanol yield [PDF]

Applied and Environmental Microbiology
Thermoanaerobacterium thermosaccharolyticum is an anaerobic and thermophilic bacterium that has been genetically engineered for ethanol production at very high yields.
Layse C. de Souza, Christopher D. Herring, Lee R. Lynd   +2 more
doaj   +2 more sources

Recent advances in site-specific transgene insertion into the maize genome using recombinases and genome editing endonucleases [PDF]

Frontiers in Plant Science
Random insertion of T-DNA into the maize genome requires the generation of many transgenic events, resulting in high cost and extensive development time. In contrast, site-specific transgene insertion (SSTI) in highly stable genomic regions emerges as an
Marcos Fernando Basso, Marcos Fernando Basso, Maisa de Siqueira Pinto, Maisa de Siqueira Pinto, Juliana Vieira Almeida Nonato, Juliana Vieira Almeida Nonato, Ricardo Augusto Dante, Ricardo Augusto Dante, Ricardo Augusto Dante, Juliana Erika de Carvalho Teixeira Yassitepe, Juliana Erika de Carvalho Teixeira Yassitepe, Juliana Erika de Carvalho Teixeira Yassitepe   +11 more
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Bioética e eugenia: pressupostos biopolíticos da manipulação genética

Griot: Revista de Filosofia, 2022
A partir da hipótese de que seres humanos modificados terão projetos de vida bem sucedidos, reflete-se quais seriam os pressupostos biopolíticos da manipulação genética na sociedade moderna. Considerando as teorias apresentadas por Michel Foucault (2005)
Luis Fernando Biasoli, André Brayner de Farias, Eduardo Borile Júnior   +2 more
doaj   +1 more source

A engenharia genética Genetic engineering

Revista de Saúde Pública, 1991
São abordados os progressos havidos com as técnicas de engenharia genética, capazes de alterar o potencial genético de um organismo, quer pela introdução, quer pela supressão de novos genes estruturais.
José Alberto Neves Candeias
doaj   +1 more source

Maize Transformation: From Plant Material to the Release of Genetically Modified and Edited Varieties

Frontiers in Plant Science, 2021
Over the past decades, advances in plant biotechnology have allowed the development of genetically modified maize varieties that have significantly impacted agricultural management and improved the grain yield worldwide.
Juliana Erika de Carvalho Teixeira Yassitepe, Juliana Erika de Carvalho Teixeira Yassitepe, Juliana Erika de Carvalho Teixeira Yassitepe, Viviane Cristina Heinzen da Silva, Viviane Cristina Heinzen da Silva, José Hernandes-Lopes, José Hernandes-Lopes, José Hernandes-Lopes, Ricardo Augusto Dante, Ricardo Augusto Dante, Ricardo Augusto Dante, Isabel Rodrigues Gerhardt, Isabel Rodrigues Gerhardt, Isabel Rodrigues Gerhardt, Fernanda Rausch Fernandes, Fernanda Rausch Fernandes, Fernanda Rausch Fernandes, Priscila Alves da Silva, Priscila Alves da Silva, Leticia Rios Vieira, Leticia Rios Vieira, Vanessa Bonatti, Vanessa Bonatti, Paulo Arruda, Paulo Arruda, Paulo Arruda   +25 more
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O fascínio dos cientistas colombianos pela engenharia genética de plantas The lure of plant genetic engineering for colombian scientists

Sociologias, 2008
A biotecnologia e a engenharia genética de plantas têm forte apelo na Colômbia, devido ao potencial que essa tecnologia proporciona para participar da nova economia do conhecimento e também como uma forma de explorar a grande biodiversidade do país ...
Christina Holmes
doaj   +1 more source

Coexpression and Transcriptome analyses identify active Apomixis-related genes in Paspalum notatum leaves

BMC Genomics, 2020
Background Paspalum notatum exhibits both sexual and apomictic cytotypes and, thus, is considered a good model for studies of apomixis because it facilitates comparative approaches. In this work, transcriptome sequencing was used to compare contrasting P.
Fernanda A. de Oliveira, Bianca B. Z. Vigna, Carla C. da Silva, Alessandra P. Fávero, Frederico P. de Matta, Ana L. S. Azevedo, Anete P. de Souza   +6 more
doaj   +1 more source