Results 91 to 100 of about 2,795,262 (398)
Knowledge Engineering for Non-engineers [PDF]
, 2010 This paper presents one approach for the innovative organization training for business analysts in developing enterprise ontologies. The underlying teaching framework is pursuing a methodology that will aid the process of knowledge structuring and practical ontology design, with emphasis on visual techniques.
openaire +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Rectifying full-counting statistics in a spin Seebeck engine [PDF]
, 2017 We investigate the rectification and negative differential effects of full-counting statistics of conjugate thermal spin transport in a spin Seebeck engine.
Chen, Xiaobin +3 more
core +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
JT9D jet engine performance deterioration [PDF]
, 1978 The analytical techniques utilized to examine the effects of flight loads and engine operating conditions on performance deterioration are presented.
Jay, A., Sallee, G. P., Todd, E. S.
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Performance evaluation of CO2 capture on using potential adsorbents in a CI engine exhaust–An experimental investigation [PDF]
, 2023 Maniarasu Ravi +2 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
AiResearch QCGAT engine performance and emissions tests [PDF]
, 1980 Results of aerodynamic performance and emission tests, conducted on a specially designed QCGAT engine in the 17,793-N (4,000 lb) thrust class, are presented. Performance of the AiResearch QCGAT engine was excellent throughout all testing.
Norgren, W. M.
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, 2012 We present a theoretical and numerical analysis of a quantum system that is capable of functioning as a heat engine. This system could be realized experimentally using cold bosonic atoms confined to a double well potential that is created by splitting a ...
Fialko, O., Hallwood, D.
core +1 more source