Results 91 to 100 of about 1,792,111 (309)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Effect of Diesel Fuel-Coconut Oil-Butanol Blends on Operational Parameters of Diesel Engine
Energies, 2020 The global concentration of greenhouse gasses in the atmosphere is increasing as well as the emissions of harmful pollutants. Utilization of liquid biofuels in combustion engines helps to reduce these negative effects. For diesel engines, the most common
Jakub Čedík +5 more
doaj +1 more source
, 1977 An arrangement for an internal combustion engine is provided in which one or more of the cylinders of the engine are used for generating hydrogen rich gases from hydrocarbon fuels, which gases are then mixed with air and injected into the remaining ...
Houseman, J.
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
United Stirling's Solar Engine Development: the Background for the Vanguard Engine [PDF]
, 1984 The development and testing resulting in the Vanguard engine and some of the characteristics of the Stirling engine based power conversion unit are described.
Holgersson, S.
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Evaluation of Motorcycles’ Handling and Stability Under Slalom Conditions
MachinesHandling and stability are crucial performance characteristics of motorcycles. However, handling and stability are always in opposition, which leads to difficulty in evaluating the comprehensive performance of a motorcycle.
Haoxuan Sun +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Improvements in petrol engine performance with ultrasonic fuel atomisation [PDF]
, 1966 Initial studies of the effect of air-fuel mixture preparation on piston engine performance have been conducted on a four cylinder 1600 cc petrol engine using conventional carburation and ultrasonic fuel atomisation.
Norster, E. R.
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source