Results 41 to 50 of about 11,940,761 (361)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Comprehensive Review of the Properties, Performance, Combustion, and Emissions of the Diesel Engine Fueled with Different Generations of Biodiesel

open access: yesProcesses, 2022
Due to the increasing air pollution from diesel engines and the shortage of conventional fossil fuels, many experimental and numerical types of research have been carried out and published in the literature over the past few decades to find a new ...
Yanhui Zhang   +4 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Improvements in petrol engine performance with ultrasonic fuel atomisation [PDF]

open access: yes, 1966
Initial studies of the effect of air-fuel mixture preparation on piston engine performance have been conducted on a four cylinder 1600 cc petrol engine using conventional carburation and ultrasonic fuel atomisation.
Norster, E. R.
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Identification of eccentricity for disc milling cutter of indexable two sided inserts

open access: yesAdvances in Mechanical Engineering, 2021
Tool eccentricity has a significant impact on machining quality, accuracy, and operation status of machine tool. It is difficult to accurately identify tool eccentricity.
Gensheng Li, Chao Xian, Hongmin Xin
doaj   +1 more source

Gaussian Process Model-Based Performance Uncertainty Quantification of a Typical Turboshaft Engine

open access: yesApplied Sciences, 2021
The gas turbine engine is a widely used thermodynamic system for aircraft. The demand for quantifying the uncertainty of engine performance is increasing due to the expectation of reliable engine performance design.
Xuejun Liu   +3 more
doaj   +1 more source

JT9D jet engine performance deterioration [PDF]

open access: yes, 1978
The analytical techniques utilized to examine the effects of flight loads and engine operating conditions on performance deterioration are presented.
Jay, A., Sallee, G. P., Todd, E. S.
core   +1 more source

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