Results 61 to 70 of about 9,256,798 (287)
The Resurgence of Software Performance Engineering [PDF]
Proceedings of the 30th on Symposium on Parallelism in Algorithms and Architectures, 2018 Today, most application developers write code without much regard for how quickly it will run. Moreover, once the code is written, it is rare for it to be reengineered to run faster. But two technology trends of historic proportions are instigating a resurgence in software performance engineering, the art of making code run fast.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
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Identification of eccentricity for disc milling cutter of indexable two sided inserts
Advances in Mechanical Engineering, 2021 Tool eccentricity has a significant impact on machining quality, accuracy, and operation status of machine tool. It is difficult to accurately identify tool eccentricity.
Gensheng Li, Chao Xian, Hongmin Xin
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Performance Engineering, PSEs and the GRID [PDF]
Scientific Programming, 2002 Performance Engineering is concerned with the reliable prediction and estimation of the performance of scientific and engineering applications on a variety of parallel and distributed hardware. This paper reviews the present state of the art in ′Performance Engineering′ for both parallel computing and meta‐computing environments and attempts to look ...
Tony Hey, Juri Papay
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
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Current status and prospects of aviation remanufacturing technology based on cold spray
Hangkong gongcheng jinzhanCold spray additive manufacturing technology，with its unique "solid-state deposition" process characteristics，has shown great application potential in the repair and remanufacturing of damaged aerospace structures.
CHI Yada +4 more
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Evaluating the performance engineering process [PDF]
Proceedings of the 2nd international workshop on Software and performance, 2000 This contribution presents a model for process improvement in the area of performance engineering, which is called performance engineering maturity model. The use of this model allows the evaluation of the level of integration and application of performance engineering.
Andreas Schmietendorf +2 more
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
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Nihon Kikai Gakkai ronbunshu, 2015 The purpose of this study is formulating the reduced integration method of damage elasto plastic constitutive model with divided back stress based on full implicit framework.
Shogo SANNOMARU +2 more
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