Results 61 to 70 of about 174,121 (317)

Current status and prospects of aviation remanufacturing technology based on cold spray

Hangkong gongcheng jinzhan
Cold spray additive manufacturing technology，with its unique "solid-state deposition" process characteristics，has shown great application potential in the repair and remanufacturing of damaged aerospace structures.
CHI Yada, CUI Minchao, LUO Ming, LI Wenya, ZHANG Dinghua   +4 more
doaj   +1 more source

Acute dermal toxicity study of new, used and laboratory aged aircraft engine oils

Toxicology Reports, 2019
There is little data available on toxicity levels of used aircraft engine oils relative to their unused (new) versions. This study was conducted to determine if new engine oils and their used versions have the potential to induce dermal irritation ...
Isaie Sibomana, Neal A. Good, Patrick T. Hellman, Lewis Rosado, David R. Mattie   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Comparative study on machinability and surface integrity of γ-TiAl alloy in laser assisted milling

Journal of Materials Research and Technology
γ-TiAl alloy, as a typical difficult-to-cut material, is considered to have great potential in aero-engine manufacturing. However, it is difficult to achieve high-quality processing of γ-TiAl alloy using traditional cutting processes, due to the room ...
Yada Chi, Zexuan Dong, Minchao Cui, Chenwei Shan, Yifeng Xiong, Dinghua Zhang, Ming Luo   +6 more
doaj   +1 more source

Experimental studies of performance and emissions in a 2/4-stroke engine [PDF]

, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityDirect Injection (DI) gasoline engines are staging a come-back because of its potential for improved fuel economy through principally the engine down-sizing
Ojapah, Mohammed
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Condition Monitoring of CI engine running on Biodiesel using Transient Process

, 2009
Various research groups across the globe have developed models for engine condition monitoring and fault diagnosis based on the data from steady state performance measurements over the last two decade. However, these performance data are not amenable for
Gu, Fengshou, Ball, Andrew, Feng Shou Gu, Gu, F., Mishra, R., Ball, A., Andrew Ball, Tesfa, Belachew, Tesfa, B., Mishra, Rakesh, B. Tesfa, R. Mishra   +11 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A novel configuration for single-crystal superalloy hollow blade manufacturing based on shell/core integral mold

Journal of Materials Research and Technology
Shell/core integral mold fabricated by additive manufacturing possess high shell/core bonding strength, which is promising to improve the dimensional accuracy and integrity of single-crystal (SX) hollow blade while improving the manufacturing efficiency.
Binqiang Wang, Zhexu Li, Kun Bu, Zhongliang Lu, Jiawei Zhang, Sheng Mou, Shengjie Ren, Haoyu Zhao   +7 more
doaj   +1 more source

Variation of Engine Performance and Emissions using Ethanol Blends

, 2010
The limited fossil fuel resources along with the increased public concerns about pollution levels have increased the need for alternative fuels for use in internal combustion engines.
Abuhabaya, Abdullah, Fieldhouse, John D.
core