Results 61 to 70 of about 12,557,310 (317)

A novel configuration for single-crystal superalloy hollow blade manufacturing based on shell/core integral mold

Journal of Materials Research and Technology
Shell/core integral mold fabricated by additive manufacturing possess high shell/core bonding strength, which is promising to improve the dimensional accuracy and integrity of single-crystal (SX) hollow blade while improving the manufacturing efficiency.
Binqiang Wang, Zhexu Li, Kun Bu, Zhongliang Lu, Jiawei Zhang, Sheng Mou, Shengjie Ren, Haoyu Zhao   +7 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Evolution mechanisms of the scratch-induced elastoplastic stress fields and crack damage in γ-TiAl alloys

Journal of Materials Research and Technology
γ-TiAl alloys are extensively utilized in aero-engine turbine blades due to their exceptional physical and mechanical properties. However, the damage mechanisms during the machining of γ-TiAl alloys remain unclear, primarily due to the complexities in ...
Zhaoqing Zhang, Kaining Shi, Yaoyao Shi, Huhu Li, Danni Lu, Yujie Kuang, Jiacheng Liu   +6 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

The interactive effect of microstructure and stress state on the microscopic damage development of aluminum alloy tailor-welded blank

Materials & Design, 2020
Ductile fracture is the most common defect in plastic forming of tailor-welded blank (TWB). Revealing the damage and fracture characteristics of welded joint is very critical for accurately predicting the fracture defect.
L. Xing, M. Zhan, P.F. Gao, M. Li, Y.D. Dong, W.W. He   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Optimization of process parameters for polishing aero-engine blade with abrasive cloth wheel considering spindle vibration and polished roughness

Scientific Reports
The vibration of machine tool spindle is very important for machining. Firstly, in order to explore the relationship between spindle vibration and process parameters, the spindle vibration acceleration when polishing aero-engine blade was measured, and ...
Chao Xian, De Liu, Hongmin Xin
doaj   +1 more source

Production of biodiesel by enzymatic transesterification of waste sardine oil and evaluation of its engine performance

Heliyon, 2017
Waste sardine oil, a byproduct of fish industry, was employed as a low cost feedstock for biodiesel production. It has relatively high free fatty acid (FFA) content (32 mg KOH/g of oil).
A. Arumugam, V. Ponnusami
semanticscholar   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source