Results 41 to 50 of about 12,557,310 (317)

Engineering the Performance [PDF]

open access: yesSocial Studies of Science, 2004
At the dawn of sound recording, recordists were mechanical engineers whose only training was on the job. As the recording industry grew more sophisticated, so did the technology used to make records, yet the need for recording engineers to use craft skill and tacit knowledge in their work did not diminish.
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Investigating the impact of abrasive tool wear on surface topography and microstructure evolution in polished GH4169G alloy through experiments and multi-scale simulations

open access: yesJournal of Materials Research and Technology
This study investigates the influence of abrasive tool wear on the surface topography and microstructure evolution of GH4169G during polishing, combining experiments and simulations to assess surface functionality.
Rui Yang   +3 more
doaj   +1 more source

Gaussian Process Model-Based Performance Uncertainty Quantification of a Typical Turboshaft Engine

open access: yesApplied Sciences, 2021
The gas turbine engine is a widely used thermodynamic system for aircraft. The demand for quantifying the uncertainty of engine performance is increasing due to the expectation of reliable engine performance design.
Xuejun Liu   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Reduced integral scheme of damaged divided back stress elasto plastic model based on full implicit algorithm

open access: yesNihon Kikai Gakkai ronbunshu, 2015
The purpose of this study is formulating the reduced integration method of damage elasto plastic constitutive model with divided back stress based on full implicit framework.
Shogo SANNOMARU   +2 more
doaj   +1 more source

Performance Engineering, PSEs and the GRID [PDF]

open access: yesScientific Programming, 2002
Performance Engineering is concerned with the reliable prediction and estimation of the performance of scientific and engineering applications on a variety of parallel and distributed hardware. This paper reviews the present state of the art in ′Performance Engineering′ for both parallel computing and meta‐computing environments and attempts to look ...
Tony Hey, Juri Papay
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Evaluating the performance engineering process [PDF]

open access: yesProceedings of the 2nd international workshop on Software and performance, 2000
This contribution presents a model for process improvement in the area of performance engineering, which is called performance engineering maturity model. The use of this model allows the evaluation of the level of integration and application of performance engineering.
Andreas Schmietendorf   +2 more
openaire   +1 more source

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