Results 41 to 50 of about 12,557,310 (317)
Engineering the Performance [PDF]
At the dawn of sound recording, recordists were mechanical engineers whose only training was on the job. As the recording industry grew more sophisticated, so did the technology used to make records, yet the need for recording engineers to use craft skill and tacit knowledge in their work did not diminish.
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
This study investigates the influence of abrasive tool wear on the surface topography and microstructure evolution of GH4169G during polishing, combining experiments and simulations to assess surface functionality.
Rui Yang +3 more
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Gaussian Process Model-Based Performance Uncertainty Quantification of a Typical Turboshaft Engine
The gas turbine engine is a widely used thermodynamic system for aircraft. The demand for quantifying the uncertainty of engine performance is increasing due to the expectation of reliable engine performance design.
Xuejun Liu +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The purpose of this study is formulating the reduced integration method of damage elasto plastic constitutive model with divided back stress based on full implicit framework.
Shogo SANNOMARU +2 more
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Performance Engineering, PSEs and the GRID [PDF]
Performance Engineering is concerned with the reliable prediction and estimation of the performance of scientific and engineering applications on a variety of parallel and distributed hardware. This paper reviews the present state of the art in ′Performance Engineering′ for both parallel computing and meta‐computing environments and attempts to look ...
Tony Hey, Juri Papay
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Evaluating the performance engineering process [PDF]
This contribution presents a model for process improvement in the area of performance engineering, which is called performance engineering maturity model. The use of this model allows the evaluation of the level of integration and application of performance engineering.
Andreas Schmietendorf +2 more
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