Results 71 to 80 of about 174,121 (317)

Engine performance and emission analysis of LPG-SI engine with the aid of artificial neural network

open access: yes, 2010
: Artificial neural network (ANN) technique is used in this analysis to estimate the performance and emission concentration of liquefied petroleum gas (LPG) spark-ignition (SI) engine. The performance indicators include fuel consumption and brake thermal
Yusaf, T.   +5 more
core   +1 more source

Experimental Study on the Production of Karanja Oil Methyl Ester and Its Effect on Diesel Engine [PDF]

open access: yes, 2012
Fast depletion of fossil fuel resources forces the extensive research on the alternative fuels. Vegetable oils edible or non edible can be a better substitute for the petroleum diesel.
N Shrivastava   +8 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

In-cylinder fuel and lubricant effects on gasoline engine friction [PDF]

open access: yes, 2007
The purpose of the research reported in this thesis was to investigate the viability and quantify the potential gains of improving fuel economy of the gasoline engine through strategic application of additives.
Smith, Oiver Mark Edward   +1 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Evolution mechanisms of the scratch-induced elastoplastic stress fields and crack damage in γ-TiAl alloys

open access: yesJournal of Materials Research and Technology
γ-TiAl alloys are extensively utilized in aero-engine turbine blades due to their exceptional physical and mechanical properties. However, the damage mechanisms during the machining of γ-TiAl alloys remain unclear, primarily due to the complexities in ...
Zhaoqing Zhang   +6 more
doaj   +1 more source

Production of Used Engine Oils with Defined Degree of Degradation in a Large-scale Device

open access: yesActa Technica Jaurinensis, 2020
Lubricant degradation by additive depletion, contamination and build-up of degradation products deteriorates lubrication performance. It can be expected that engine oil degradation also has an impact on performance parameters. Engine development tends to
Adam Agocs   +6 more
doaj   +1 more source

Studies on SI engine simulation and air/fuel ratio control systems design [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.More stringent Euro 6 and LEV III emission standards will immediately begin execution on 2014 and 2015 respectively.
Bai, Yang, Yang Bai
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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