Results 91 to 100 of about 9,256,798 (287)

Engine performance and emission analysis of LPG-SI engine with the aid of artificial neural network

open access: yes, 2010
: Artificial neural network (ANN) technique is used in this analysis to estimate the performance and emission concentration of liquefied petroleum gas (LPG) spark-ignition (SI) engine. The performance indicators include fuel consumption and brake thermal
Yusaf, T.   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Vibration suppression and surface roughness control in flexible blade polishing: modeling, simulation and optimization

open access: yesEngineering Science and Technology, an International Journal
In the flexible polishing process for blisk, tool vibration represents a critical factor governing surface integrity and machining stability. However, comprehensive modeling of the dynamic behavior of flexible polishing tools and its quantitative ...
Chao Xian   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Effect of ultrasonic vibration-assisted milling on surface quality of carbon fiber reinforced polymer

open access: yesJournal of Materials Research and Technology
This paper studies the effect and mechanisms of ultrasonic vibration-assisted machining on the surface quality of carbon fiber reinforced polymer (CFRP), based on the kinematic characteristics of ultrasonic vibration-assisted milling.
Yukun Zhang, Junxue Ren, Jinhua Zhou
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Mechanical response and machining defects evolution of γ-TiAl under ultrasonic vibration-assisted milling

open access: yesJournal of Materials Research and Technology
With low density and high specific strength, γ-TiAl alloys are attractive lightweight replacements for superalloys in thin-walled aeroengine hot-section components, yet their intrinsic brittleness causes severe machining defects that limit practical use.
Yifei You   +6 more
doaj   +1 more source

T-S Fuzzy Model Based H-Infinity Control for 7-DoF Automobile Electrohydraulic Active Suspension System

open access: yesJournal of Control Science and Engineering, 2017
This paper presents a double loop controller for a 7-DoF automobile electrohydraulic active suspension via T-S fuzzy modelling technique. The outer loop controller employs a modified H-infinity feedback control based on a T-S fuzzy model to provide the ...
Chenyu Zhou   +3 more
doaj   +1 more source

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