Results 101 to 110 of about 930,385 (313)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Reduce wear and control friction for copper-based powder metallurgy wet friction material by optimizing porosity, surface roughness and surface texture

open access: yesAlexandria Engineering Journal
Copper-based powder metallurgy materials are common friction materials in many fields such as aviation, high-speed railway and automobiles because of their good thermal conductivity, stable friction performance and relatively high mechanical properties ...
Zhi Chen   +6 more
doaj   +1 more source

Developments in REDES: The Rocket Engine Design Expert System [PDF]

open access: yes
The Rocket Engine Design Expert System (REDES) was developed at NASA-Lewis to collect, automate, and perpetuate the existing expertise of performing a comprehensive rocket engine analysis and design.
Davidian, Kenneth O.
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Mechanism of heterogeneous substrate stimulating growth for nickel-based single crystal superalloy

open access: yesJournal of Materials Research and Technology
Minimizing the deviation of single-crystal (SX) primary orientation can significantly enhance the yield rate, service life, and performance of turbine blades or castings.
Binqiang Wang   +5 more
doaj   +1 more source

The digital simulation of a turbo-charged diesel engine [PDF]

open access: yes, 1969
A mathematical simulation of a six cylinder four stroke water cooled diesel engine is described and then used to study the changes in performance caused by variations of engine paramters and operating conditions.
Hodgetts, D., Shroff, H. D.
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

AiResearch QCGAT engine performance and emissions tests [PDF]

open access: yes, 1980
Results of aerodynamic performance and emission tests, conducted on a specially designed QCGAT engine in the 17,793-N (4,000 lb) thrust class, are presented. Performance of the AiResearch QCGAT engine was excellent throughout all testing.
Norgren, W. M.
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Orbit transfer vehicle engine study. Volume 1: Executive summary [PDF]

open access: yes
The orbit transfer vehicle (OTV) engine study provided parametric performance, engine programmatic, and cost data on the complete propulative spectrum that is available for a variety of high energy, space maneuvering missions.

core   +1 more source

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