Results 31 to 40 of about 965,816 (315)

Review of Advancement in Variable Valve Actuation of Internal Combustion Engines

open access: yesApplied Sciences, 2020
The increasing concerns of air pollution and energy usage led to the electrification of the vehicle powertrain system in recent years. On the other hand, internal combustion engines were the dominant vehicle power source for more than a century, and they
Zheng Lou, Guoming Zhu
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A model-based approach for sustainability and value assessment in the aerospace value chain

open access: yesAdvances in Mechanical Engineering, 2015
In the aerospace industry, systems engineering practices have been exercised for years, as a way to turn high-level design objectives into concrete targets on system functionality (e.g. range, noise, and reliability).
Marco Bertoni   +2 more
doaj   +1 more source

Technological Change from Analog to Digital

open access: yesAnnals of Business Administrative Science, 2014
Brusoni, Prencipe, and Pavitt (2001) posited that the digitization of aircraft engine control systems in the early 1980s caused loose organizational coupling.
Yuichiro MUKAI
doaj   +1 more source

Method for improving the fuel efficiency of a gas turbine engine [PDF]

open access: yes, 1985
An energy recovery system is provided for an aircraft gas turbine engine of the type in which some of the pneumatic energy developed by the engine is made available to support systems such as an environmental control system.
Coffinberry, G. A.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Study on vibration response characteristics of turbine blade for turbo-charger

open access: yesNihon Kikai Gakkai ronbunshu, 2019
In the mechanical design of a turbine blade for an automotive turbo-charger, it is pointed out that the mistuning effect caused by the difference of the casting condition should be considered.
Yasutomo KANEKO   +4 more
doaj   +1 more source

Apparatus for improving the fuel efficiency of a gas turbine engine [PDF]

open access: yes, 1983
An energy recovery system is provided for an aircraft gas turbine engine of the type in which some of the pneumatic energy developed by the engine is made available to support systems such as an environmental control system.
Coffinberry, G. A.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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