Results 41 to 50 of about 965,816 (315)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Control of High-Load Compressor Stator Corner Flow by Blade Slotting

International Journal of Aerospace Engineering
Flow separation often occurs in the stator corner of a compressor, especially in a highly loaded compressor. Therefore, there are multiple methods for flow control, such as blade slotting, which uses the pressure difference between the pressure surface ...
Enbo Liu, Zhenggui Zhou, Huan Zheng
doaj   +1 more source

Effectiveness of the Speed Reduction Strategy on Exhaust Emissions and Fuel Oil Consumption of a Marine Generator Engine for DC Grid Ships

Journal of Marine Science and Engineering, 2022
Recent developments in power electronics, energy storage systems, and renewable energy; increased market demands for more efficient and cleaner electric power to meet stricter environmental regulations; and development in gigawatt (GW)-class DC (direct ...
Van Chien Pham, Hanseok Kim, Jae-Hyuk Choi, Antony J. Nyongesa, Jongsu Kim, Hyeonmin Jeon, Won-Ju Lee   +6 more
doaj   +1 more source

MULTIAGENT SYSTEMS ENGINEERING [PDF]

International Journal of Software Engineering and Knowledge Engineering, 2001
This paper describes the Multiagent Systems Engineering (MaSE) methodology. MaSE is a general purpose, methodology for developing heterogeneous multiagent systems. MaSE uses a number of graphically based models to describe system goals, behaviors, agent types, and agent communication interfaces.
Scott A. DeLoach, Mark F. Wood, Clint H. Sparkman   +2 more
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Effect of Break Edge Configuration on the Aerodynamics of Anti-Ice Jet Flow

EPJ Web of Conferences, 2015
One of the components of a turboprop gas turbine engine is the Front Bearing Structure (FBS) which leads air into the compressor. FBS directly encounters with ambient air, as a consequence ice accretion may occur on its static vanes.
Tatar V., Yildizay H., Aras H.
doaj   +1 more source

Environmental Impact Assessment, on the Operation of Conventional and More Electric Large Commercial Aircraft [PDF]

, 2013
Global aviation is growing exponentially and there is a great emphasis on trajectory optimization to reduce the overall environmental impact caused by aircraft. Many optimization techniques exist and are being studied for this purpose.
Lawson, Craig P., Sabatini, Roberto, Seresinhe, R.   +2 more
core   +1 more source