Results 51 to 60 of about 25,670,789 (354)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

New perspectives on Web search engine research [PDF]

open access: yes, 2012
Purpose–The purpose of this chapter is to give an overview of the context of Web search and search engine-related research, as well as to introduce the reader to the sections and chapters of the book.
Lewandowski, Dirk
core  

The atmospheric steam engine as energy converter for low and medium temperature thermal energy [PDF]

open access: yes, 2013
Many industrial processes and renewable energy sources produce thermal energy with temperatures below 100 °C. The cost-effective generation of mechanical energy from this thermal energy still constitutes an engineering problem.
Müller, G.
core   +1 more source

A model-based approach for sustainability and value assessment in the aerospace value chain

open access: yesAdvances in Mechanical Engineering, 2015
In the aerospace industry, systems engineering practices have been exercised for years, as a way to turn high-level design objectives into concrete targets on system functionality (e.g. range, noise, and reliability).
Marco Bertoni   +2 more
doaj   +1 more source

Technological Change from Analog to Digital

open access: yesAnnals of Business Administrative Science, 2014
Brusoni, Prencipe, and Pavitt (2001) posited that the digitization of aircraft engine control systems in the early 1980s caused loose organizational coupling.
Yuichiro MUKAI
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Gas-turbine diagnostics using artificial neural-networks for a high bypass ratio military turbofan engine [PDF]

open access: yes, 2004
The Tristar aircraft, operated by the Royal Air Force, fly many thousands of hours per year in the transport and air-to-air refuelling roles. A large amount of engine data is recorded for each of the Rolls-Royce RB211-524B4 engines: it is used to aid ...
Singh, Riti   +3 more
core   +1 more source

Study on vibration response characteristics of turbine blade for turbo-charger

open access: yesNihon Kikai Gakkai ronbunshu, 2019
In the mechanical design of a turbine blade for an automotive turbo-charger, it is pointed out that the mistuning effect caused by the difference of the casting condition should be considered.
Yasutomo KANEKO   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Multi-disciplinary conceptual design of future jet engine systems [PDF]

open access: yes, 2010
This thesis describes various aspects of the development of a multi-disciplinary aero engine conceptual design tool, TERA2020 (Techno-economic, Environmental and Risk Assessment for 2020), based on an explicit algorithm that considers: engine ...
Kyprianidis, Konstantinos G.
core  

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