Results 21 to 30 of about 84,751 (254)
mAbs, 2023 The blood-brain barrier (BBB) largely excludes antibodies from entering the central nervous system, thus limiting the potential of therapeutic antibodies to treat conditions such as neurodegenerative diseases and neuro-psychiatric disorders.
Jason Tien +13 more
doaj +1 more source
EURADWASTE’22 Paper – Host rocks and THMC processes in DGR
EPJ Nuclear Sciences & Technologies, 2022 Deep geological disposal aims to contain and isolate radioactive waste from the biosphere. Repository systems are made of multiple barriers working together, typically comprising the natural geological barrier provided by the repository host rock and its
Levasseur Séverine +6 more
doaj +1 more source
An analysis of barriers for the introduction of Systems Engineering
Procedia CIRP, 2019 Abstract Industry faces challenges for the development of complex technical products. Systems Engineering (SE) is expected to solve these. Within the last years, the awareness for SE has drastically risen in German industry companies in the sectors of automotive engineering, machinery and plant engineering and electrical devices.
Lukas Bretz +2 more
openaire +1 more source
On the hydro-mechanical behaviour of MX80 bentonite-based materials
Journal of Rock Mechanics and Geotechnical Engineering, 2017 Bentonite-based materials have been considered in many countries as engineered barrier/backfilling materials in deep geological disposal of high-level radioactive waste. During the long period of waste storage, these materials will play an essential role
Yu-Jun Cui
doaj +1 more source
Disposal of High-Level Nuclear Waste in Deep Horizontal Drillholes
Energies, 2019 Spent nuclear fuel and high-level radioactive waste can be disposed in deep horizontal drillholes in sedimentary, metamorphic or igneous rocks. Horizontal drillhole disposal has safety, operational and economic benefits: the repository is deep in the ...
Richard A. Muller +7 more
doaj +1 more source
Approaches to Disposal of Nuclear Waste
Energies, 2022 We present a concise mini overview on the approaches to the disposal of nuclear waste currently used or deployed. The disposal of nuclear waste is the end point of nuclear waste management (NWM) activities and is the emplacement of waste in an ...
Michael I. Ojovan, Hans J. Steinmetz
doaj +1 more source
Increasing understanding and confidence in THM simulations of Engineered Barrier Systems [PDF]
Environmental Geotechnics, 2020 Previous studies on the modelling of coupled thermo-hydro-mechanical (THM) processes in bentonite-based engineered barrier systems (EBSs) showed the sensitivity of the output quantities to changes in the input parameters. To investigate the effects of uncertainties on the modelling results, to improve the understanding of the coupled processes active ...
Schäfers, Annika +11 more
openaire +4 more sources
ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT [PDF]
, 2004 The purpose of this report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The abstraction model is used in the total system performance assessment for the license application (TSPA LA) to assess the ...
openaire +9 more sources
Frontiers in Microbiology, 2023 Inflammatory bowel disease (IBD) is becoming more common in the Western world due to changes in diet-related microbial dysbiosis, genetics and lifestyle.
Kathryn Prame Kumar +2 more
doaj +1 more source
ENGINEERED BARRIER SYSTEM FEATURES, EVENTS, AND PROCESSES [PDF]
, 2005 This analysis report is one of the technical reports containing documentation of the Environmental Radiation Model for Yucca Mountain, Nevada (ERMYN), a biosphere model supporting the total system performance assessment (TSPA) for the license application (LA) for the Yucca Mountain repository. This analysis report describes the development of biosphere
+9 more sources