Results 91 to 100 of about 2,612,478 (275)

Introducing monitoring and automation in cartilage tissue engineering, toward controlled clinical translation [PDF]

, 2011
The clinical application of tissue engineered products requires to be tightly connected with the possibility to control the process, assess graft quality and define suitable release criteria for implantation.
Santoro, Rosaria
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Optical Mapping of Impulse Propagation in Engineered Cardiac Tissue [PDF]

, 2008
Cardiac tissue engineering has a potential to provide functional, synchronously contractile tissue constructs for heart repair, and for studies of development and disease using in vivo–like yet controllable in vitro settings.
Iyer, Rohin K., Park, Hyoungshin, Radisic, Milica, Fast, Vladimir G., Sharifov, Oleg F., Vunjak-Novakovic, Gordana   +5 more
core   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Temporal effects of mechanical loading on deformation-induced damage in skeletal muscle tissue [PDF]

, 2010
Mechanical loading of soft tissues covering bony prominences can cause skeletal muscle damage, ultimately resulting in a severe pressure ulcer termed deep tissue injury.
S. Loerakker, Bader, D.L., Rijpkema, JJM Koo, K. Nicolay, Baaijens, F. P. T., C. W. J. Oomens, Strijkers, GJ Gustav, Oomens, CWJ Cees, Loerakker, S., Oomens, C.W.J., Nicolaij, K Klaas, Strijkers, G. J., Baaijens, FPT Frank, Rijpkema, J. J. M., Stekelenburg, A., G. J. Strijkers, Strijkers, G.j., Oomens, C. W. J., Loerakker, S Sandra, Stekelenburg, A Anke, D. L. Bader, Baaijens, F.P.T., Rijpkema, J.J.M., Bader, D. L., J. J. M. Rijpkema, F. P. T. Baaijens, Bader, DL Dan, A. Stekelenburg, Nicolay, K.   +28 more
core   +2 more sources

Advances and Prospects in Using Induced Pluripotent Stem Cells for 3D Bioprinting in Cardiac Tissue Engineering

Reviews in Cardiovascular Medicine
Background: Cardiovascular diseases remain one of the leading causes of death worldwide. Given the limited self-repair capacity of cardiac tissue, cardiac tissue engineering (CTE) aims to develop strategies and materials for repairing ...
Baoluo Du, Ziqiang Dai, Huan Wang, Zhipeng Ren, Dianyuan Li   +4 more
doaj   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]

, 2012
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
core   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Spatial and temporal patterns of bone formation in ectopically pre-fabricated, autologous cell-based engineered bone flaps in rabbits [PDF]

, 2008
Biological substitutes for autologous bone flaps could be generated by combining flap pre-fabrication and bone tissue engineering concepts. Here, we investigated the pattern of neotissue formation within large pre-fabricated engineered bone flaps in ...
Pierer, Gerhard, Oliver Scheufler, Galli, Raffaele, Scheufler, Oliver, Braccini, Alessandra, David J. Wendt, Heberer, Michael, Michael Heberer, Gerhard Pierer, Raffaele Galli, Dirk J. Schaefer, Gasser, Juerg A., Jürg A. Gasser, Martin, Ivan, Ivan Martin, Jaquiery, Claude, Claude Jaquiery, Wendt, David J., Alessandra Braccini, Schaefer, Dirk J.   +19 more
core   +1 more source