Results 161 to 170 of about 82,857 (303)
, 2004 The restoration of normal cardiac function can potentially be achieved by functional tissue constructs grown in vitro by using differentiated or progenitor cells, biomaterial scaffolds and bioreactors. Engineered tissues can also serve as high-fidelity models for basic studies of cells and tissues, in response to gene alterations, drugs, hypoxia, or ...
Vunjak-Novaković, Gordana +2 more
openaire +1 more source
Advanced Healthcare Materials, EarlyView.This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre +3 more
wiley +1 more source
Real‐Time 3D Ultrasound Imaging with an Ultra‐Sparse, Low Power Architecture
Advanced Healthcare Materials, EarlyView.This article presents a novel, ultra‐sparse ultrasound architecture that paves the way for wearable real‐time 3D imaging. By integrating a unique convolutional array with chirped data acquisition, the system achieves high‐resolution volumetric scans at a fraction of the power and hardware complexity.
Colin Marcus +9 more
wiley +1 more source
Accomplishments and challenges in stem cell imaging in vivo. [PDF]
, 2019 Stem cell therapies have demonstrated promising preclinical results, but very few applications have reached the clinic owing to safety and efficacy concerns.
Bose, Rajendran JC, Mattrey, Robert F
core
Advanced Healthcare Materials, EarlyView.A multilayered small‐caliber vascular scaffold combining electrospinning and 4‐axis printing is developed and biofunctionalized with marine sulfated polysaccharides from Holothuria tubulosa. The resulting construct exhibits enhanced hemocompatibility, tunable mechanical properties, and supports endothelial and smooth muscle cell adhesion and ...
Gabriele Obino +9 more
wiley +1 more source
An electro-mechanical bioreactor providing physiological cardiac stimuli [PDF]
, 2013 In cardiac tissue engineering it has been widely demonstrated the fundamental role of physical stimuli in improving structural and functional properties of the engineered cardiac constructs.
Audenino, Alberto +5 more
core
Advanced Healthcare Materials, EarlyView.This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
Acute Response of Engineered Cardiac Tissue to Pressure and Stretch.
Cells Tissues Organs, 2023 Donoghue L, Graham C, Sethu P.
europepmc +1 more source
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
Advanced Materials, EarlyView.A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Nature CommunicationsEngineered human cardiac tissues have been utilized for various biomedical applications, including drug testing, disease modeling, and regenerative medicine. However, the applications of cardiac tissues derived from human pluripotent stem cells are often
Sungjin Min +20 more
doaj +1 more source