Mini-hearts for disease modeling and drug testing - process optimization versus biological functionality. [PDF]
Hecking J +3 more
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Mechanisms of rectified gap junctional coupling enhancing pacemaking activity of biologically engineered pacemaker cells. [PDF]
Li Y +8 more
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Advances in In Vitro Vascularization of Engineered Tissues: From Microvessel Formation to Hepatic Tissue Integration. [PDF]
Huang YH, Ono A, Sudo R.
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Crossbow Bioreactors for Studying the Effects of Time-Varying Mechanical Preload and Afterload on Engineered Cardiac Tissues. [PDF]
Helfer A, Strash N, Patsy M, Bursac N.
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Progress and challenges in transplantation of human pluripotent stem cell derived cardiomyocytes for cardiac therapy. [PDF]
Bain JD, Barrs RW, Mei Y.
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This book chapter will explore the area of cardiac tissue engineering and biomaterials used for cardiac cell therapy. After describing the pathology of heart disease and presenting the motivation for pursuing tissue engineering for the heart, the chapter outlines some of the current clinical treatments used to correct the loss of function resulting ...
Devang Odedra +5 more
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Cardiac muscle tissue engineering
IEEE Engineering in Medicine and Biology Magazine, 2003Cell-based therapy has emerged as a novel approach for replacing heart muscle, which is known not to regenerate after injury such as that caused by infarction or reconstructive surgery. Two types of cell-based therapies have been employed: injection of isolated cells or the implantation of in-vitro-grown cardiac muscle tissue equivalents In the first ...
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Strategies in cardiac tissue engineering
ANZ Journal of Surgery, 2010AbstractIn heart failure, post‐myocardial infarction and some congenital cardiac anomalies, organ transplantation is the only effective cure. Shortage of organ donors and complications of orthotopic heart transplant remain major challenges to the modern field of transplantation.
Richard, Tee +3 more
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Engineering Three-Dimensional Vascularized Cardiac Tissues
Tissue Engineering Part B: Reviews, 2022Heart disease is one of the largest burdens to human health worldwide and has very limited therapeutic options. Engineered three-dimensional (3D) vascularized cardiac tissues have shown promise in rescuing cardiac function in diseased hearts and may serve as a whole organ replacement in the future.
Marcus Alonso Cee, Williams +4 more
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Bioreactors for Cardiac Tissue Engineering
Advanced Healthcare Materials, 2018AbstractThe advances in biotechnology, biomechanics, and biomaterials can be used to develop organ models that aim to accurately emulate their natural counterparts. Heart disease, one of the leading causes of death in modern society, has attracted particular attention in the field of tissue engineering.
Jesus Paez‐Mayorga +7 more
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