Results 91 to 100 of about 185,762 (313)

Computer technologies in the education of mechanical engineers

open access: yesJournal of Physics: Conference Series, 2021
Abstract The paper shows an example of using an algorithm for studying the mechanism by analytical methods in the process of teaching students the basics of the theory of mechanisms and machines. This method is also applicable for cam and gear mechanisms.
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The analysis of engineering adaptation to global challenges and strategic planning for the future

open access: yesSustainable Engineering and Innovation
A global shift towards green and sustainable solutions requires adapting emerging engineering technologies to evolve novel engineering solutions. Such solutions are incumbent to meet the emerging challenges ranging from smart infrastructural needs to ...
Krystyna Heti   +4 more
doaj   +1 more source

Cloud computing and context-awareness: A study of the adapted user experience

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Today, mobile technology is part of everyday life and activities and the mobile ecosystems are blossoming, with smartphones and tablets being the major ...
Grønli, Tor-Morten
core  

A Review on Fog Computing Systems [PDF]

open access: yes, 2022
The current decade has witnessed a wide deployment of Internet of Things (IoT) technology in various application domains, and its pervasive role will continue to strengthen in the future.
Farhoud Hosseinpour   +5 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

From analogy-making to modelling : the history of analog computing as a modelling technology [PDF]

open access: yes
Today, modern computers are based on digital technology. However, during the decades after 1940, digital computers were complemented by the separate technology of analog computing.
Care, Charles
core  

The national cloud computing strategy [PDF]

open access: yes, 2013
Executive summary On 5 October 2012 the Prime Minister announced that the Australian Government would develop a National Cloud Computing Strategy.

core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy