Results 101 to 110 of about 185,762 (313)

The broken dream of pervasive sentient ambient calm invisible ubiquitous computing [PDF]

open access: yes, 2015
Date of Acceptance: 15/12/2014We dreamt of technology becoming invisible, for our wants and needs to be primary and the tools we use for making them a reality to become like a genie, a snap of the fingers and ta daa, everything is realised.
Quigley, Aaron J.   +5 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Applying Agile Software Engineering On Medical Ubiquitous Computing (MUC) [PDF]

open access: yes, 2016
Nowadays, people are involved in using computation capabilities to meet their daily life needs although most of the time they may be unaware as to how this actually happens.
Al Sarraj, Wael F., Nazli, Mohammed N
core  

9th International Conference on Multimedia and Ubiquitous Engineering and the 10th International Conference on Future Information Technology

open access: yes, 2015
This volume brings together contributions representing the state-of-the-art in new multimedia and future technology information research, currently a major topic in computer science and electronic engineering.
Chao, Han-Chieh   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Affective Computing: Recent Advances, Challenges, and Future Trends

open access: yesIntelligent Computing
Affective computing is a rapidly growing multidisciplinary field that encompasses computer science, engineering, psychology, neuroscience, and other related disciplines.
Guanxiong Pei   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Corrigendum

open access: yesInternational Journal of Nanomedicine, 2012
Jalil MA, Moongfangklang N, Innate K, Mitatha S, Ali J, Yupapin PP. Molecular network topology and reliability for multipurpose diagnosis. Int J Nanomedicine.
Jalil MA   +5 more
doaj  

Computing for construals in distributed participatory design : principles and tools [PDF]

open access: yes, 2009
Distributed participatory design aspires to standards of inclusivity and humanity in introducing technology to the workplace that are hard to attain. The demands it makes upon the development and use of computing technology are particularly topical, as ...
Beynon, Meurig, Chan, Zhan En
core  

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