Results 81 to 90 of about 1,247,044 (291)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A hierarchy model on the research fields of cyberspace security technology
网络与信息安全学报, 2015 Cyberspace security is an interdisciplinary subject involved with computer science and technology,in-formation and communication engineering,control science and engineering and cryptography.It has an explicit and in-depth discipline connotation.First,the
Bin-xing FANG
doaj +3 more sources
Design and Realization of Brake System in Heavy Engineering Vehicle based on Web Theory
Jixie chuandong, 2015 In order to solve the problems of the design and simulation analysis software portability and interoperability deficiencies of existing heavy engineering vehicle brake system,by using the Browser/Server and Client/Server hybrid structure,combined the JSP.
Ma Zhanbao, Wang Jing
doaj
Enhancing e-Infrastructures with Advanced Technical Computing: Parallel MATLAB® on the Grid [PDF]
, 2008 MATLAB® is widely used within the engineering and scientific fields as the language and environment for technical computing, while collaborative Grid computing on e-Infrastructures is used by scientific communities to deliver a faster time to solution ...
Chakravarti, A +6 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Explaining the AMST Model: Using Arts, Maths, Science, and Technology in an Upgraded Problem-Based Learning Approach [PDF]
Journal of Systemics, Cybernetics and Informatics, 2017 Recent literature has touted the importance of the Science, Technology, Engineering, and Mathematics (STEM) curriculum model as the best way to develop a problem-based inquiry in the technology-rich, globally-connected 21st century learning environment ...
Georgia Daleure
doaj
Big Data and cloud computing: innovation opportunities and challenges
International Journal of Digital Earth, 2017 Big Data has emerged in the past few years as a new paradigm providing abundant data and opportunities to improve and/or enable research and decision-support applications with unprecedented value for digital earth applications including business ...
Chaowei Yang +4 more
doaj +1 more source
Digital, material and networked: some emerging themes for SET education [PDF]
, 2015 Boundaries between the digital and material worlds are becoming blurred as the internet increasingly connects us to things as well as people and information.
Davies, Sarah-Jane +2 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Meaning and Vision of Mimic Computing and Mimic Security Defense
Dianxin kexue, 2014 To facilitate high-performance and high-security computing, a technology system based on mimic computing（MC）and mimic security defense（MSD）was proposed. The proposed system focused on both the multi-dimensional reconfigurable and functional architecture ...
Jiangxing Wu
doaj +2 more sources