Results 61 to 70 of about 185,762 (313)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The Application of Web-Based Scientific Computing System in Innovation and Entrepreneurship

open access: yesDiscrete Dynamics in Nature and Society, 2022
In the past ten years, the number of newly added labor forces in China has continued to grow. At the same time, with the increase in the number of university candidates, the number of university employments is also increasing.
Tingli Cheng
doaj   +1 more source

Cloud computing models [PDF]

open access: yes, 2013
Thesis (S.M. in Engineering and Management)--Massachusetts Institute of Technology, Engineering Systems Division, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (p. 79-80).Information Technology has always been considered a
Gorelik, Eugene
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

REQUIREMENTS ENGINEERING FOR CLOUD COMPUTING ADAPTIVE MODEL

open access: yesJournal of ICT, 2016
The easy access and flexibility provided by cloud computing have made various types of organizations use this technology as an alternative solution. However, the decision to use the cloud technology sometimes ignores the basic aspects related to the ...
Kridanto Surendro   +2 more
doaj  

A grid computing framework for commercial simulation packages

open access: yes, 2007
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An increased need for collaborative research among different organizations, together with continuing advances in communication technology and computer ...
Mustafee, Navonil
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

New trends in networking, computing, e-learning, systems sciences, and engineering

open access: yes, 2015
This book includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of Computer Science, Informatics, and Systems Sciences, and Engineering. It includes selected papers form the
Sobh, Tarek, Elleithy, Khaled
core   +1 more source

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