Results 41 to 50 of about 1,247,044 (291)

Science Gateway for Distributed Multiscale Course Management in e-Science and e-Learning - Use Case for Study and Investigation of Functionalized Nanomaterials

open access: yes, 2015
The current tendency of human learning and teaching is targeted to development and integration of digital technologies (like cloud solutions, mobile technology, learning analytics, big data, augmented reality, natural interaction technologies, etc.). Our
Bekenov, Lev   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Quantum computing: a property of matter at nano-scale level that can transform civil engineering to quantum civil engineering

open access: yesDiscover Computing
Civil engineering problems are inherently complex and computationally intensive, often requiring advanced methods to analyze large-scale systems and nonlinear interactions. Addressing these challenges requires next-generation computing paradigms that can
IfeOlorun Olofin
doaj   +1 more source

Exploring the Intersection of Software Engineering and Mobile Technology from 2010 to 2021: A Review of Recent Research

open access: yesJournal of Innovation Information Technology and Application, 2023
This paper presents a comprehensive review of recent research on the intersection of software engineering and mobile technology. The review method involves a systematic literature search and analysis of relevant research articles.
S M Nazmuz Sakib
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A précis of philosophy of computing and information technology [PDF]

open access: yes, 2009
The authors recently finished a comprehensive chapter on “Philosophy of Computing and Information Technology” for the forthcoming (fall 2009) Philosophy of Technology and Engineering Sciences (Ed.: A.
Brey, Philip, Soraker, Johnny Hartz
core   +1 more source

Biomedical Informatics Applications for Precision Management of Neurodegenerative Diseases [PDF]

open access: yes, 2018
Modern medicine is in the midst of a revolution driven by “big data,” rapidly advancing computing power, and broader integration of technology into healthcare. Highly detailed and individualized profiles of both health and disease states are now possible,
Jimenez-Maggoria, Gustavo   +3 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Artificial Intelligence in Law: Studies and Future Insights

open access: yesMehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, 2020
In recent years, as a result of the development of internet technology, increasing the computing power of computers and storing millions of data with cloud computing, artificial intelligence studies have been increasing rapidly.
Tülay TURAN   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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