Results 51 to 60 of about 13,444 (166)
Energies, 2019 The parallel system is a kind of scientific research method based on an artificial system and computational experiments, which can not only reflect the dynamic process of the real system but also optimize its control process in real time. Given the rapid
Zhicheng Lin +4 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Design and Realization of Brake System in Heavy Engineering Vehicle based on Web Theory
Jixie chuandong, 2015 In order to solve the problems of the design and simulation analysis software portability and interoperability deficiencies of existing heavy engineering vehicle brake system,by using the Browser/Server and Client/Server hybrid structure,combined the JSP.
Ma Zhanbao, Wang Jing
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Advances in Mechanical Engineering, 2018 The purpose of this article is to improve the convergence efficiency of the traditional efficient global optimization method. Furthermore, we try a graphics processing unit–based parallel computing method to improve the computing efficiency of the ...
Bing Xu, Yong Cai
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Meaning and Vision of Mimic Computing and Mimic Security Defense
Dianxin kexue, 2014 To facilitate high-performance and high-security computing, a technology system based on mimic computing（MC）and mimic security defense（MSD）was proposed. The proposed system focused on both the multi-dimensional reconfigurable and functional architecture ...
Jiangxing Wu
doaj +2 more sources
A hierarchy model on the research fields of cyberspace security technology
网络与信息安全学报, 2015 Cyberspace security is an interdisciplinary subject involved with computer science and technology,in-formation and communication engineering,control science and engineering and cryptography.It has an explicit and in-depth discipline connotation.First,the
Bin-xing FANG
doaj +3 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Integrating Web Technologies with Augmented Reality
International Journal of Research and Applied TechnologyThis study aims to provide a comprehensive review of the integration between web technologies and augmented reality (AR) in engineering and computing contexts.
Agis Abhi Rafdhi
doaj +1 more source