Results 51 to 60 of about 185,762 (313)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Artificial Intelligence in Law: Studies and Future Insights
Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, 2020 In recent years, as a result of the development of internet technology, increasing the computing power of computers and storing millions of data with cloud computing, artificial intelligence studies have been increasing rapidly.
Tülay TURAN +2 more
doaj +1 more source
Disruptive technology business models in cloud computing [PDF]
, 2010 Thesis (S.M. in System Design and Management)--Massachusetts Institute of Technology, Engineering Systems Division, System Design and Management Program, 2010.Cataloged from PDF version of thesis.Includes bibliographical references.Cloud computing, a ...
Krikos, Alexis Christopher
core
The Design and Implementation of Middleware for Application Development within Honeybee Computing Environment [PDF]
, 2016 Computing technology is now moving from ubiquitous computing into advanced ubiquitous computing environment. An advanced ubiquitous environment is an extension of ubiquitous environment that improve connectivity between devices.
Mohd Zin, Abdullah; Universiti Kebangsaan Malaysia +2 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Emerging Intelligent Technologies in Computer-Aided Engineering
Journal of Advanced Computational Intelligence and Intelligent Informatics, 2000 Competition generated the requirement of quick decisions at engineering activities. As a consequence, application of advanced computer modeling in engineering design needs application of intelligent computer methods to assist human decision making.
László Horváth, Imre J. Rudas
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Innovations and advances in computing, informatics, systems sciences, networking and engineering
, 2015 Innovations and Advances in Computing, Informatics, Systems Sciences, Networking and Engineering This book includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of Computer
Sobh, Tarek, Elleithy, Khaled
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Adopting the Appropriate Performance Measures for Soft Computing-based Estimation by Analogy [PDF]
, 2020 Soft Computing based estimation by analogy is a lucrative research domain for the software engineering research community. There are a considerable number of models proposed in this research area.
Jawawi, Dayang N. A.; Software Engineering Department, School of Computing, Faculty of Engineering, Universit Teknologi Malaysia, Johor Bahru, Malaysia +4 more
core +1 more source