Results 161 to 170 of about 250,405 (253)

The Sea Lamprey (Petromyzon marinus) Invasion: The Construction of an Invasive Animal Threatening a "Healthy" Great Lakes Ecosystem. [PDF]

J Hist Med Allied Sci
Bijman V.
europepmc   +1 more source

Indo-Singapore trade in services: Enhancing co-operation [PDF]

Aditi Mody, Arpita Mukherjee, Nisha Taneja, Ruchika Sachdeva   +3 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Implementation of a Deep Learning System for Detection and Classification of Lumpy Skin Disease in Cattle: Enhancing Precision and Efficiency in Veterinary Diagnostics. [PDF]

Vet Med Sci
Pal M, Behera S, Mohapatra RK, Branda F, Mersal GAM, Mishra S, El-Bahy SM, Pattnaik G, Pattanaik S, Ali MS, Mishra A, Tuglo LS, Youssef M.   +12 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Green radiotherapy: aitro survey on sustainability awareness among Italian radiation therapists. [PDF]

Tech Innov Patient Support Radiat Oncol
Votta C, Lastrucci A, Iosca N, Bassani D, Bernabucci L, Bertolini M, Galdieri C, Pasini D, Pisoni V, Zucca A, Lambertini D, Cornacchione P.   +11 more
europepmc   +1 more source

The Continuing Historical Legacy of Dominick “Toby” Graham [PDF]

, 2015
David Zimmerman
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Classifying Patient Complaints Using Artificial Intelligence-Powered Large Language Models: Cross-Sectional Study.

J Med Internet Res
Koh SWC, Wong ERN, Tan JCM, van der Lubbe SCC, Goh JC, Ching ESY, Chia IWY, Low SH, Ang PY, Quek Q, Motani M, Valderas JM.   +11 more
europepmc   +1 more source

A study protocol for a pragmatic pre-post trial to determine the feasibility and effectiveness of a novel co-designed service to support health and wellbeing of older carers of older people. [PDF]

PLoS One
Lalor A, Slatyer S, Burton E, Bryant C, Oliveira D, Khushu A, Brusco N, Layton N, Lee DA, Cash B, Allen J, Licciardi L, Hill KD.   +12 more
europepmc   +1 more source