Results 171 to 180 of about 1,008,712 (292)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

An axiomatic system engineering design method based on NSGA-II algorithm applied to complex systems. [PDF]

Sci Rep
Zhang X, Zhang Q, Zhao Q, Zhao S, Zhao Y, Guo Y, Zhao Z, Song L.   +7 more
europepmc   +1 more source

Suggesting an Analysis Framework for Korea STEAM Programs in the Perspective of Engineering Design

, 2018
LeeDongYoung, Younkyeong Nam
openalex   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A chaotic arithmetic optimization algorithm with Cauchy perturbation and differential evolution for engineering design problems. [PDF]

Sci Rep
Liu Y, Tang Y, Hua C.
europepmc   +1 more source

Improving Activity Requirements in Open Plan Office Spaces by Using Different Acoustic Design Elements: Engineering Studies and Consultation Center as a Case Study [PDF]

Sanaa Abdelghany Eldyasty Ahmed Eid, Asmaa N. El-Badrawy, Alaa El-Eashy   +2 more
openalex   +1 more source

Semirational design and engineering of grapevine glucosyltransferases for enhanced activity and modified product selectivity [PDF]

, 2019
Rakesh S. Joshi, Johanna Trinkl, Annika Haugeneder, Katja Härtl, Katrin Franz‐Oberdorf, Ashok P. Giri, Thomas Hoffmann, Wilfried Schwab   +7 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Aerospace Bionic Robotics: BEAM-D Technical Standard of Biomimetic Engineering Design Methodology Applied to Mechatronics Systems. [PDF]

Biomimetics (Basel)
Cornejo J, Weitzenfeld A, Baca J, García Cena CE.   +3 more
europepmc   +1 more source

Method Development for Computer Aided Engineering for Aircraft Conceptual Design

, 2008
Adrien Bérard
openalex   +1 more source