Results 31 to 40 of about 4,649,067 (302)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Hydrology, 2018 The authors explore the uncertainty implied in the estimation of changes in flood frequency due to climate change at the basins of the Cedar River and Skunk River in Iowa, United States.
Felipe Quintero +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
Mathematics, 2023 In large engineering firms, most design projects are undertaken by teams of individuals. From the perspective of senior management, the overall project team must maintain scheduling, investment and return on the investment discipline while solving ...
Judson Estes, Vijitashwa Pandey
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim +8 more
wiley +1 more source
Modelling iteration in engineering design [PDF]
, 2007 This paper examines design iteration and its modelling in the simulation of New Product Development (NPD) processes. A framework comprising six perspectives of iteration is proposed and it is argued that the importance of each perspective depends upon ...
Clarkson, PJ, Eckert, CM, Wynn, DC
core +1 more source
, 2014 Designing complex engineering systems, such as an aircraft or an aero-engine, is immensely challenging. Formal Systems Engineering (SE) practices are widely used in the aerospace industry throughout the overall design process to minimise the overall ...
Bertoni, M. +3 more
core +3 more sources
Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
Journal of Facade Design and Engineering, 2014 Corresponding author: Paulo L. Carvalho, School of Architecture, University of Minho, Campus de Azurém, Guimarães, Portugal. Tel.: +351 253 510 500; E-mail: paulo.carvalho@arquitectura.uminho.pt A reinforced glass folded structure has been developed ...
Paulo L. Carvalho +2 more
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