Results 51 to 60 of about 4,649,067 (302)
TEC – Thin Environmental Cladding
Journal of Facade Design and Engineering, 2014 Corresponding author: Alan Tomasi, Group R&D Project Manager, Permasteelisa S.p.A., viale E. Mattei 21/23 | 31029 Vittorio Veneto, Treviso, Italy. Tel.: +39 0438 505207; E-mail: a.tomasi@permasteelisagroup.com; www.permasteelisagroup.com Permasteelisa ...
Alan Tomasi +4 more
doaj
Turkish Journal of Forestry, 2017 Engineering design is a systematic, intelligent process in which designers generate, evaluate, and specify concepts for devices, systems, or processes whose form and function achieve clients’ objectives or users’ needs while satisfying a specified set of
Kenan Ok
doaj +1 more source
Engineering design project : series 1 [PDF]
, 2017 This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Problem Based Learning and its use on the Automotive Engineering Design Course at Coventry University [PDF]
, 1998 The Automotive Engineering Design course at Coventry University has been in operation since October 1989 and has earned a reputation for creating able engineers well prepared for industry. When originally conceived, a problem led approach to learning was
Robotham, AJ
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Embedding object-oriented design in system engineering [PDF]
, 1999 The Unified Modeling Language (UML) is a collection of techniques intended to document design decisions about software. This contrasts with systems engineering approaches such as for exampleStatemate and the Yourdon Systems Method (YSM), in which the ...
D Harel, RJ Wieringa
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ADOPT: An augmented set-based design framework with optimisation
Design Science, 2019 During the early stages of any system design, a thorough exploration of the design space can prove to be challenging and computationally expensive. The challenges are further exacerbated when dealing with complex systems, such as an aircraft, due to the ...
Alex Georgiades +3 more
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source