Results 61 to 70 of about 1,011,340 (268)

Emotional design engineering for packaging of olive oil using machine learning techniques

Cogent Engineering
Consumer behaviour, and therefore purchase intentions, are affected by the visual elements of packaging. This is particularly important for products in the agri-food sector, especially for olive oil.
Ana de las Heras, Francisco Zamora-Polo, Antonio Ferramosca, Amalia Luque   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Enhanced Henry Gas Solubility Optimization for Solving Data and Engineering Design Problems

Eng
Many engineering design problems are formulated as constrained optimization tasks that are nonlinear and nonconvex, and often treated as black boxes. In such cases, metaheuristic algorithms are attractive because they can search complex design spaces ...
Jamal Zraqou, Ayman Alnsour, Riyad Alrousan, Hussam N. Fakhouri, Niveen Halalsheh   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Potential for innovative massive building envelope systems – Scenario development towards integrated active systems

Journal of Facade Design and Engineering, 2015
In order to generate possible scenarios about future developments of massive constructions, this paper explains the developmental paths on the basis of individual materials of clay/brick as well as concrete/lightweight concrete/aerated concrete and sand ...
Ulrich Knaack
doaj  

A Multi-Strategy Improved Honey Badger Algorithm for Engineering Design Problems

Algorithms
A multi-strategy improved honey badger algorithm (MIHBA) is proposed to address the problem that the honey badger algorithm may fall into local optimum and premature convergence when dealing with complex optimization problems.
Tao Han, Tingting Li, Quanzeng Liu, Yourui Huang, Hongping Song   +4 more
doaj   +1 more source

Design for Values in Engineering

, 2014
Values have probably always played a role in engineering design. However, in current practices and design methods, the attention for values in engineering design tends to be implicit and unsystematic. Establishing Design for Values in engineering would require overcoming this situation.
openaire   +4 more sources

Perception of Complexity in Engineering Design

Systems Engineering, 2021
This paper evaluates perception of complexity in a novel explanatory model that relates product performance and engineering effort. Complexity is an intermediate factor with two facets: it enables desired product performance but also requires effort to achieve.
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source