Results 81 to 90 of about 4,649,067 (302)

Supply-Demand-Based Optimization: A Novel Economics-Inspired Algorithm for Global Optimization

IEEE Access, 2019
A novel metaheuristic optimization algorithm, named supply-demand-based optimization (SDO), is presented in this paper. SDO is a swarm-based optimizer motivated by the supply-demand mechanism in economics.
Weiguo Zhao, Liying Wang, Zhenxing Zhang
doaj   +1 more source

Blending arts and sciences: gimmick or necessity? [PDF]

, 2008
The shortage of degree qualified engineers in the UK is well documented. On the other hand the surplus of art and design graduates is growing. Whilst acknowledging the shortage in engineering graduates, there is also the need to recognise the breadth and
Bradley, Michael D., Karamanoglu, Mehmet, Prior, Stephen D.   +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

SciTech News Volume 71, No. 1 (2017) [PDF]

, 2017
Columns and Reports From the Editor 3 Division News Science-Technology Division 5 Chemistry Division 8 Engineering Division Aerospace Section of the Engineering Division 9 Architecture, Building Engineering, Construction and Design Section of the ...

core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Potential for innovative massive building envelope systems – Scenario development towards integrated active systems

Journal of Facade Design and Engineering, 2015
In order to generate possible scenarios about future developments of massive constructions, this paper explains the developmental paths on the basis of individual materials of clay/brick as well as concrete/lightweight concrete/aerated concrete and sand ...
Ulrich Knaack
doaj  

SciTech News Volume 71, No. 3 (2017) [PDF]

, 2017
Columns and Reports From the Editor.........................3 Division News Science-Technology Division....5 Chemistry Division....................8 Conference Report, Marion E, Sparks Professional Development Award Recipient..9 Engineering Division......

core   +1 more source

Introducing systems engineering to industrial design engineering students with hands-on experience [PDF]

, 2005
The article presents an innovative educational project to introduce systems engineering to third year students in industrial design engineering at the University of Twente. In a short period the students are confronted with new technology, namely sensors
Bonnema, G. Maarten, Houten, Fred J.A.M. van, Lutters-Weustink, Ilanit F.   +2 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Creativity in Mass-Education Contexts [PDF]

, 2006
This paper discusses a learning framework (working title: ‘fog framework’) that has been developed in response to the challenge of teaching creative subjects in a mass-education context.
Anusas, M.
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