Results 81 to 90 of about 4,699,625 (307)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Engineering design project : series 2 [PDF]
, 2017 This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.
core
RE-DESIGNING THE LIBRARY FOR DESIGN ENGINEERING
Proceedings of the Canadian Engineering Education Association (CEEA), 2011 This paper relates our experience at the Engineering & Science Library at Queen’s University, melding Library resources into the design engineering curriculum in the Faculty of Applied Science. Effective library support of design engineering comprises people, curriculum, collections and assessment.
Murphy, Sharon, Saleh, Nasser
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
South African Journal of Industrial Engineering, 2016 This paper synthesises an overview of various models of the engineering design process with an overview of the most relevant theories within the field of creativity studies to conclude that (i) creativity plays a role throughout the engineering design ...
Oosthuizen, L., Vlok, P. J.
doaj +1 more source
OntoEng: A design method for ontology engineering in information systems [PDF]
, 2009 This paper addresses the design problem relating to ontology engineering in the discipline of information systems. Ontology engineering is a realm that covers issues related to ontology development and use throughout its life span.
Al-Debei, MM, Fitzgerald, G
core
System engineering approach applied to Galileo system [PDF]
, 2010 Developing a localization system, with more precise performances than GPS that guarantees Europe autonomy is a complex challenge that ESA and a large number of European economical actors of space industry were decided to meet.
Bouchired, Steven +1 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The 24 hour challenge: creating a multidiscipline environment for design and entrepreneurship in engineering and design. Enhancing Employability through Enterprise Education [PDF]
, 2014 This Innovation and Creative Exchange (ICE) is an inter-school enterprise opportunity exclusively for second year Engineering and Design students at the University of Huddersfield.
Power, Jess
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source