Results 101 to 110 of about 4,699,625 (307)
Diagnostic systems in DEMO: engineering design issues
The diagnostic systems of DEMO that are mounted on or near the torus, whether intended for the monitoring and control functions of the engineering aspects or the physics behaviour of the machine, will have to be designed to suit the hostile nuclear ...
Todd, T N
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Elicitation of Preference Structure in Engineering Design
Engineering design processes, which inherently involve multiple, often conflicting criteria, can be broadly classified into synthesis and analysis processes.
J. K. Tan
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
High-Speed Real-Time Simulators for Engineering Design
The use of computer simulations is now an established technique in engineering design. Many of these simulations are used to predict the expected behavior of systems that are not yet built, or of existing systems in modes of operation, such as ...
R. E. Crosbie, N. G. Hingorani
doaj
In model-based product development, engineering models representing specific parts a product from diverse aspects and resolutions are used to reduce cost and lead time while systematically reducing design alternatives.
Hitoshi KOMOTO +2 more
doaj +1 more source
Managing engineering design in complex supply chains [PDF]
The trend towards organising design, development and manufacture via supply chains, rather than predominantly in-house, poses major challenges for design management. Procurement methods based on adversarial competitive tendering are generally unsuited to
Potter, Stephen, Roy, Robin
core
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
SciTech News Volume 71, No. 3 (2017) [PDF]
Columns and Reports From the Editor.........................3 Division News Science-Technology Division....5 Chemistry Division....................8 Conference Report, Marion E, Sparks Professional Development Award Recipient..9 Engineering Division......
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