Results 91 to 100 of about 4,699,625 (307)
Supply-Demand-Based Optimization: A Novel Economics-Inspired Algorithm for Global Optimization
IEEE Access, 2019 A novel metaheuristic optimization algorithm, named supply-demand-based optimization (SDO), is presented in this paper. SDO is a swarm-based optimizer motivated by the supply-demand mechanism in economics.
Weiguo Zhao, Liying Wang, Zhenxing Zhang
doaj +1 more source
Blending arts and sciences: gimmick or necessity? [PDF]
, 2008 The shortage of degree qualified engineers in the UK is well documented. On the other hand the surplus of art and design graduates is growing. Whilst acknowledging the shortage in engineering graduates, there is also the need to recognise the breadth and
Bradley, Michael D. +2 more
core
Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
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Design for Values in Engineering
, 2014 Values have probably always played a role in engineering design. However, in current practices and design methods, the attention for values in engineering design tends to be implicit and unsystematic. Establishing Design for Values in engineering would require overcoming this situation.
openaire +4 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
SciTech News Volume 71, No. 1 (2017) [PDF]
, 2017 Columns and Reports From the Editor 3 Division News Science-Technology Division 5 Chemistry Division 8 Engineering Division Aerospace Section of the Engineering Division 9 Architecture, Building Engineering, Construction and Design Section of the ...
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Perception of Complexity in Engineering Design
Systems Engineering, 2021 This paper evaluates perception of complexity in a novel explanatory model that relates product performance and engineering effort. Complexity is an intermediate factor with two facets: it enables desired product performance but also requires effort to achieve.
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Journal of Facade Design and Engineering, 2015 In order to generate possible scenarios about future developments of massive constructions, this paper explains the developmental paths on the basis of individual materials of clay/brick as well as concrete/lightweight concrete/aerated concrete and sand ...
Ulrich Knaack
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source