Results 71 to 80 of about 4,699,625 (307)
Engineering Design and Society [PDF]
SSRN Electronic Journal, 2017 As a discipline, engineering is rooted in mathematics and natural sciences; as a practice, it is social at its core. Social science is a more recent development than the society that it seeks to document and understand. Bringing social science into engineering design has its pros and cons.
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A preliminary study of the nonlinearity of adhesive point-fixings in structural glass facades
Journal of Facade Design and Engineering, 2014 Corresponding author: Jonas Dispersyn, Laboratory for Research on Structural Models (LMO), Department of Structural Engineering, Faculty of Engineering and Architecture, Ghent University, Ghent, Belgium.
Jonas Dispersyn +3 more
doaj
Approaches to the teaching of design : an engineering subject centre guide [PDF]
, 2009 This booklet seeks to provide a resource for all those with an interest in design, and the education and training of engineering students to carry out the design process.
Mclaren, Andrew
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A completely transparent, adhesively bonded soda-lime glass block masonry system
Journal of Facade Design and Engineering, 2015 A pioneering, all transparent, self-supporting glass block facade is presented in this paper. Previously realized examples utilize embedded metal components in order to obtain the desired structural performance despite the fact that these elements ...
F. Oikonomopoulou +3 more
doaj
Weight–strength optimization of wooden household chairs based on member section size
Maderas: Ciencia y Tecnología, 2022 Weight-strength optimization of wooden household chairs was performed based on the member section size in this study. Member section sizes of the Scotch pine (Pinus sylvestris) and Oriental beech (Fagus orientalis) chairs were optimized and resulting re-
Ersan Güray, Erkan Ceylan, Ali Kasal
doaj
A practical application for machine design education
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018 Machine design is perhaps the most important course for Mechanical Engineering students. There are many diverse approaches to the design education in universities worldwide.
Hüseyin R. BÖRKLÜ +3 more
doaj +1 more source
Issues Affecting Security Design Pattern Engineering [PDF]
, 2013 Security Design Patterns present the tried and tested design decisions made by security engineers within a well documented format. Patterns allow for complex security concepts, and mechanisms, to be expressed such that non domain experts can make use of ...
de Muijnck-Hughes, Jan, Duncan, Ishbel
core
Designing an online part-time Master of Philosophy with Problem Oriented Engineering [PDF]
, 2009 The paper reports on the application of Problem Oriented Engineering (POE) to the design of a highly innovative post-graduate research programme for the Open University, UK, a world leader in supported distance higher education.
Hall, Jon G., Rapanotti, Lucia
core +1 more source