Results 131 to 140 of about 9,039,452 (379)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Analysis of international graduate programmes structures for engineering education [PDF]

, 2010
This article traces the evolution of graduate study in Engineering in Ireland over three decades. Very few studies have shown the different norms and structures of graduate programmes in Ireland.
Brabazon, Dermot, Karazi, Shadi, Murphy, Gary, Naher, Sumsun   +3 more
core  

Engineering Education in the United States at the End of the Century [PDF]

, 1900
Ira O. Baker
openalex   +1 more source

A systematic review of research on the flipped learning method in engineering education

British Journal of Educational Technology, 2018
: The purpose of this article is to describe the current state of knowledge and practice in the flipped learning approach in engineering education and to provide guidance for practitioners by critically appraising and summarizing existing research.
A. Karabulut-Ilgu, N. J. Cherrez, C. Jahren   +2 more
semanticscholar   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Report of the joint committee on engineering education [PDF]

, 1918

openalex   +1 more source

The core components of education 4.0 in higher education: Three case studies in engineering education

Computers & electrical engineering, 2021
Jhonattan Miranda, Christelle Navarrete, J. Noguez, J. Molina-Espinosa, M. Ramírez-Montoya, Sergio A. Navarro-Tuch, M. Bustamante-Bello, J. Rosas-Fernández, A. Molina   +8 more
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

On the need for an anticolonial perspective in engineering education and practice. [PDF]

Nat Commun, 2023
Mitra S, Sarkar S, Ganguli-Mitra A.
europepmc   +1 more source

On the Value of the Classics in Engineering Education [PDF]

, 1910
Charles Proteus Steinmetz
openalex   +1 more source