Results 141 to 150 of about 3,330,587 (398)

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

ETHICS IN PROGNOSTICS AND HEALTH MANAGEMENT

open access: yesInternational Journal of Prognostics and Health Management, 2019
As we enter an era where intelligent systems are omnipresent and where they also permeate Prognostics and Health Management ( PHM ), the discussion of moral machines or ethics in engineering will inevitably engulf PHM as well.
Kai Goebel, Brian Smith, Anupa Bajwa
doaj   +1 more source

Teaching Engineering Ethics [PDF]

open access: yes, 2015
Instruction in engineering ethics is an important aspect of professional development. For universities, it is an element of program assessment and is considered for accreditation.
Watkins, Steve Eugene
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Davis Discussant Remarks - APPE 2010 [PDF]

open access: yes, 2010
Remarks by Dr. Michael Davis as part of the panel "Engineering and Social Justice: What are the Difficulties, What are the Possibilities? as part of a mini conference at the Association for Practical and Professional Ethics Annual Meeting entitled ...
Davis, Michael
core   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

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