Results 111 to 120 of about 5,028,054 (300)
Describing 'generic' graduate engineer skills
, 2018 Project-Based Learning, Qualitative Research, Grounded Theory, Creativity Being able to describe skills effectively is essential for teaching and enabling students to learn skills. A previous study [1], investigating the development of real industrial problem solving skills in a taught Masters course, found inadequate skill descriptions were a ...
Shawcross, JK, Ridgman, Tom W
openaire +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
EDUCATIONAL TECHNOLOGIES IN TRAINING OF CHEMICAL PROCESS ENGINEERS
Высшее образование в России, 2016 Technification of educational process is a stable development trend for institutions of higher education. Exemplified by the course “General chemical engineering”, implementation of modular and context educational technology is shown.
Farida T. Shageeva, Vasily G. Ivanov
doaj
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Engineering next generation vascularized organoids
AtherosclerosisOrganoids are self-organizing 3D cell culture models that are valuable for studying the mechanisms underlying both development and disease in multiple species, particularly, in humans. These 3D engineered tissues can mimic the structure and function of human organs in vitro.
Nicolas Werschler +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Local microenvironment reactive zone engineering promotes water activation
Materials Reports: EnergyBeyond conventional electrocatalyst engineering, recent studies have demonstrated the effectiveness of manipulating the local reaction environment to enhance the performance of electrocatalytic reactions.
Jian Luo +6 more
doaj +1 more source
Manned simulations of the SRMS in SIMFAC [PDF]
, 1978 SIMFAC is a general purpose real-time simulation facility currently configured with an Orbiter-like Crew Compartment and a Displays and Controls (D and C) Subsystem to support the engineering developments of the Space Shuttle Remote Manipulator (SRMS ...
Lippay, A. L. +2 more
core +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source