Results 131 to 140 of about 5,076,354 (301)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
MOSS, an evaluation of software engineering techniques [PDF]
An evaluation of the software engineering techniques used for the development of a Modular Operating System (MOSS) was described. MOSS is a general purpose real time operating system which was developed for the Concept Verification Test (CVT) program ...
Bounds, J. R., Pruitt, J. L.
core +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Образование и наукаIntroduction. The article presents the results of a study of the actual problem in applying a transdisciplinary approach as a modern educational resource that contributes to improving the efficiency and productivity of students’ learning outcomes based ...
A. B. Iskakova, K. A. Nurumzhanova
doaj +1 more source
Drag Reduction: Back to Basics [PDF]
Aeronautical design engineering for general aviation aircraft considers the iteration of wind tunnel test data are lift, weight, drag, and thrust as the basic balancing factor in drag reduction ...
Nicks, O. W.
core +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Space solar power systems [PDF]
Studies were done on the feasibility of placing a solar power station called POwersat, in space. A general description of the engineering features are given as well as a brief discussion of the economic ...
Toliver, C.
core +1 more source