Results 41 to 50 of about 64,245 (240)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Design and Fabrication of Heterojunctions of Thiosemicarbazones and Metal Oxide Nanoparticles in Search of Their Medicinal Activity

Engineering Proceedings
Thiosemicarbazone (TSC) derivatives and their complexes have emerged as versatile medicinal agents. Now, the focus has shifted to targeted drug delivery and here, the application of nanotechnology is being explored.
Ekhlakh Veg, Seema Joshi, Tahmeena Khan
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A Recommendation System for E-Commerce Products Using Collaborative Filtering Approaches

Engineering Proceedings
The objective of this article is to recommend products using association rule mining from an E-commerce site. This helps us to recommend products through utilizing the filtering concept. In this article, we use the Apriori and FP-Growth algorithms.
Neelamadhab Padhy, Sridev Suman, T Sanam Priyadarshini, Subhalaxmi Mallick   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Impact of Different Drying Techniques on the Nutritional Components of Plum Tomatoes

Engineering Proceedings
Tomatoes are currently regarded as one of the world’s major vegetable crops. Tomatoes have a significant economic impact on the earnings of many growers worldwide. The tomato is one of the most widely grown vegetables in the world and is ranked second in
Kazeem Ajadi Ibraheem, Abdullahi Nuraddeen Bakori   +1 more
doaj   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Design and Application of an Energy Management System Based on Artificial Intelligence Technology

Engineering Proceedings
In response to the increasingly severe energy consumption problem and to promote energy saving and emission reduction, this study aims to design and apply an energy management system platform based on artificial intelligence (AI) technology.
Hongye Lin, Xuanying Bai, Chun Li, Shenghan Xu, Haibin Xu, Zne-Jung Lee, Yun Lin, Qunshan Zhou, Jingxun Cai   +8 more
doaj   +1 more source

Effect of seed-beds on the cultivation of Radicchio (Cichorium intybus L., Rubifolium group) [PDF]

, 2016
The use of raised beds (i.e., ridged soil layers) to cultivate vegetables can improve soil quality, crop performance, water use and even reduce soil erosion.
Bietresato, Marco, Bortolini, Lucia
core   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source