Results 41 to 50 of about 3,155,901 (278)

An Integrated Entropy–MAIRCA Approach for Multi-Dimensional Strategic Classification of Agricultural Development in East Africa

open access: yesMathematics
Agricultural development is vital for East Africa’s economic growth, yet the region faces significant disparities and systemic barriers. A critical problem exists due to the lack of an integrated quantitative framework to systematically comparing ...
Chia-Nan Wang   +3 more
doaj   +1 more source

Risk management in civil engineering [PDF]

open access: yesGrađevinski Materijali i Konstrukcije, 2023
Risk is involved in the whole lifecycle of a structure: design, construction, utilization, and demolition. There is a close connection between reliability and risk.
Mašović Snežana   +4 more
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Towards an integrated perspective on fleet asset management: engineering and governance considerations [PDF]

open access: yes, 2008
The traditional engineering perspective on asset management concentrates on the operational performance the assets. This perspective aims at managing assets through their life-cycle, from technical specification, to acquisition, operation including ...
Kivits, Rob   +3 more
core   +2 more sources

Improving Recruitment and Retention: A Management Framework to Utilize DMAIC and Kaizen for Student Support in Engineering Education

open access: yesTrends in Higher Education
The Clay N. Hixson Student Success Center within the College of Engineering at Tennessee Tech University has undergone a transformative upgrade by integrating the Define, Measure, Analyze, Improve, and Control (DMAIC) framework with select Kaizen ...
Kumar Yelamarthi   +2 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

OntoMaven: Maven-based Ontology Development and Management of Distributed Ontology Repositories [PDF]

open access: yes, 2013
In collaborative agile ontology development projects support for modular reuse of ontologies from large existing remote repositories, ontology project life cycle management, and transitive dependency management are important needs.
Paschke, Adrian
core  

The suitability of MSP for engineering infrastructure [PDF]

open access: yes, 2020
This paper arose from empirical investigations of practitioner views of both governance and program definitions together with investigations of practitioner reference documents.
McGrath, Stephen   +1 more
core   +2 more sources

Constrained Scheduling Optimization of Improved LLH Resources for Engineering Management [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences
To investigate how to maximize the benefits of engineering projects through effective scheduling strategies in the context of limited resources, this study develops a high-level heuristic strategy that leverages deep reinforcement learning algorithms ...
Lijun Liu, Luxia Ouyang
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

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