Results 111 to 120 of about 1,661,640 (282)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Search engine optimization

, 2010
The paper deals with the importance of web page optimization. Internet and its characteristics are shown in the beginning of this paper, as the main source of obtaining information. Web pages should have all the necessary information that people are seeking and should also be ranged as high as possible in the search engines.
openaire   +3 more sources

Net saving improvement of capacitor banks in power distribution systems by increasing daily size switching number: A comparative result analysis by artificial intelligence

The Journal of Engineering
This paper studies the effect of the number of switching (NOS) per day of capacitor banks on loss reduction in radial distribution systems. To this aim, the daytime (more precisely, 24 h) is divided into different numbers of time segments (equal to the ...
Omid Sadeghian, Ashkan Safari
doaj   +1 more source

Multidisciplinary design optimization: An emerging new engineering discipline [PDF]

This paper defines the Multidisciplinary Design Optimization (MDO) as a new field of research endeavor and as an aid in the design of engineering systems.
Sobieszczanski-Sobieski, Jaroslaw
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Bat algorithm based on kinetic adaptation and elite communication for engineering problems

CAAI Transactions on Intelligence Technology
The Bat algorithm, a metaheuristic optimization technique inspired by the foraging behaviour of bats, has been employed to tackle optimization problems.
Chong Yuan, Dong Zhao, Ali Asghar Heidari, Lei Liu, Shuihua Wang, Huiling Chen, Yudong Zhang   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

EDECO: An Enhanced Educational Competition Optimizer for Numerical Optimization Problems

Biomimetics
The Educational Competition Optimizer (ECO) is a newly proposed human-based metaheuristic algorithm. It derives from the phenomenon of educational competition in society with good performance.
Wenkai Tang, Shangqing Shi, Zengtong Lu, Mengying Lin, Hao Cheng   +4 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source