Results 121 to 130 of about 160,456 (265)
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2014 In this paper, we consider a combinatorial optimization problem in a cyclic production system treating identical jobs. The cyclic production system possesses m machines, and every job consists of n tasks.
Rei HINO, Yoshiyuki KARUNO
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Optimizing mechanical component design with population-based metaheuristics
Open EngineeringThis study presents a comprehensive comparison of two population-based metaheuristic algorithms, differential evolution (DE) and particle swarm optimization (PSO), applied to the optimization of mechanical component design under both single-objective and
Nakkiew Warisa +3 more
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FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
GEO: Generative Engine Optimization
Proceedings of the 30th ACM SIGKDD Conference on Knowledge Discovery and Data MiningThe advent of large language models (LLMs) has ushered in a new paradigm of search engines that use generative models to gather and summarize information to answer user queries. This emerging technology, which we formalize under the unified framework of generative engines (GEs), can generate accurate and personalized responses, rapidly replacing ...
Pranjal Aggarwal +5 more
openaire +2 more sources
Computer Engineering 3KB3: Optimization, Vol. 2
, 1993 Custom Courseware prepared by John Bandler for Computer Engineering 3KB3: Computational Methods II, for the fall 1994 session. Some materials were previously available in early 1993 as individual texts used in Computer Engineering 4KC3: Simulation and ...
Bandler, John
core
Bayesian Optimization (BO) is a foundational strategy in engineering design optimization for efficiently handling black-box functions with many constraints and expensive evaluations.
Ahmed, Faez, Yu, Rosen T., Picard, Cyril
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Learning-based ship design optimization approach
, 2012 With the development of computer applications in ship design, optimization, as a powerful approach, has been widely used in the design and analysis process.
Philip Sayer +5 more
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Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source