Results 91 to 100 of about 10,591 (277)
Advanced Science, EarlyView.We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua +6 more
wiley +1 more source
NEW APPROACHES TO THE FORMATION OF LEGAL COMPETENCE IN ENGINEERING PEDAGOGY
Высшее образование в России, 2017 The paper has been prepared on the basis of its authors' great experience in working in various areas at a technical university. It represents the result of long-term research and reflections on improving the legal support for engineering activities ...
S. V. Barabanova, R. I. Zinurova
doaj
Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy
Advanced Science, EarlyView.A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru +2 more
wiley +1 more source
ENGINEERING PEDAGOGY: FROM COLLABORATIVE LEARNING TO UNIVERSAL SYNERGY
Высшее образование в России, 2017 The labor market imposes new requirements to a contemporary engineer: he should be capable of working in groups and managing other people, ready for teamwork, independent decision making, setting and solving new professional problems, independent ...
P. N. Osipov
doaj
Advanced Science, EarlyView.This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley +1 more source
Distributed Constructionism in Engineering Tutorials: Requirements Engineering
, 2021 Constructionism - a process where knowledge is constructed through manipulation of realworld things - is a natural pedagogical approach for the engineering discipline, where 'making' is a fundamental aspect of professional practice.
Rajan, Tharun, Browne, Chris
core
Advanced Science, EarlyView.SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang +33 more
wiley +1 more source
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Advanced Science, EarlyView.Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
TRAINING RESEARCH AND ENGINEERING ELITE FOR RUSSIAN DEFENSE INDUSTRY
Высшее образование в России, 2016 The paper deals with the problem of qualified personnel shortage in science intensive spheres of economy and analyzes the factors contributing to raising of the quality of young specialist training and further employment in high-tech industry.
Igor B. Fedorov, Valentin E. Medvedev
doaj
Высшее образование в России, 2022 An important factor in providing security in technosphere is the level of professional competency of the engineers - Bachelor’s, Master’s and Specialist’s degree holders, - who design, create and operate objects of the infrastructure.
Yury V. Trofimenko +2 more
doaj