Results 91 to 100 of about 689,327 (298)

An Alternative to Videos for Lecture Preparation in a Flipped First-Year Engineering Computing Course [PDF]

, 2016
Gregory Bucks, Kathleen Ossman
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Traffic Engineering Analysis in the Preparation and Reconstruction of Urban Roads [PDF]

, 2018
Tibor Schlosser, Peter Schlösser
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Digital support of production small business preparation in engineering [PDF]

, 2019
V. F. Bulavin, T.G. Bulavina, V V Yahrichev, A.S. Stepanov, Aleksey A. Frolov   +4 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Chiroptical switching and strong circularly polarized luminescence in peptide supramolecular assemblies

Nature Communications
Peptide-based materials offer unique advantages for constructing supramolecular chiral systems due to their bioactivity and intrinsic chirality. However, precise control over the expression, transfer, and amplification of chirality from the molecular to ...
Xin Li, Qingquan Han, Xianbao Li, Rui Li, Anhe Wang, Sen Liang, Yutao Sang, Jieling Li, Yajie Tian, Yang Yang, Qi Li, Shuo Bai, Junbai Li   +12 more
doaj   +1 more source

Preparation and Application of Magnetic Responsive Materials in Bone Tissue Engineering

, 2020
Song Li, Changling Wei, Yonggang Lv
openalex   +1 more source

Preparation and Characterization of Collagen–Hydroxyapatite Composite Used for Bone Tissue Engineering Scaffold [PDF]

, 2003
Lingrong Liu, Lihai Zhang, Bai-zhi Ren, Fujun Wang, Qiqing Zhang   +4 more
openalex   +1 more source

CREATION OF A SOLID PRODUCT MODEL IN AN AUTOMATED DESIGN SYSTEM - EFFECTIVE PREPARATION OF THE STUDENT FOR FUTURE ENGINEERING ACTIVITIES

, 2022
Nadia Bilytska, Aleksandra Hetman
openalex   +2 more sources