Results 61 to 70 of about 703,793 (262)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Biomedical Data Sharing Among Researchers: A Study from Jordan

open access: yesJournal of Multidisciplinary Healthcare, 2020
Lina Al-Ebbini,1 Omar F Khabour,2 Karem H Alzoubi,3 Almuthanna K Alkaraki4 1Department of Biomedical Systems and Informatics Engineering, Hijjawi for Engineering Technology, Yarmouk University, Irbid 21163, Jordan; 2Department of Medical Laboratory ...
Al-Ebbini L   +3 more
doaj  

Convergences, transferts et intégrations entre sciences du langage, sciences et ingénierie en temps de guerre et de guerre froide (1941-1966)

open access: yesRevue d’Histoire des Sciences Humaines, 2015
This paper aims at examining the impact of war sciences on language sciences during the World War II. I will assume that the interaction between war sciences (engineering and sciences) and language sciences should be distinguished from the war effort ...
Jacqueline Léon
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

数据科学与工程:大数据时代的新兴交叉学科

open access: yes大数据, 2015
There are some characteristics for IT development in the big data era:the real-life applications are the driving force for innovation; open sourcing accelerates innovation,and the advancement in hardware lay the foundation for innovation.The data ...
Aoying Zhou, Weining Qian, Changbo Wang
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Attitudes and Behavior of Ajman University of Science and Technology Students Towards the Environment [PDF]

open access: yesIAFOR Journal of Education, 2016
This study examined the attitudes and behavior of Ajman University of Science and Technology (AUST) students towards the environment according to their gender and college. The research was based on a descriptive approach.
Rasha Abdel Raman
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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