Results 81 to 90 of about 3,645,822 (281)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Investigation of effect of pump rotational speed on performance and detection of cavitation within a centrifugal pump using vibration analysis

open access: yesHeliyon, 2019
Cavitation is an essential problem that occurs in any pump. It highly contributes to deteriorating the performance of the pump. In industrial applications, it is important to detect and decrease the effect of the cavitation in pumps.
Ahmed Ramadhan Al-Obaidi
doaj   +1 more source

Bacteria Use Type IV Pili to Walk Upright and Detach from Surfaces [PDF]

open access: yes, 2010
1. Department of Bioengineering, California Nano Systems Institute,University of California, Los Angeles, CA 90024, USA. 2. Department of Chemical and Biomolecular Engineering, University of Houston, Houston, TX 77204, USA. 3.
Conrad, Jacinta C.   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Blockchain-IoT and optioneering driven framework for smart water management in emerging urban areas

open access: yesiScience
Summary: We present a blockchain-enabled IoT framework for transforming intermittent water distribution networks (WDNs) into continuous supply in Edakochi, Kerala, India, which faces critical hydraulic and climatic challenges.
Nibi Kulangara Velayudhan   +5 more
doaj   +1 more source

Erratum: 89 Bridging Cell Biology and Engineering Sciences: Interdisciplinary Team-based Training in Computational Pathology - ERRATUM. [PDF]

open access: yesJ Clin Transl Sci, 2023
Tan MJT   +7 more
europepmc   +1 more source

The Bologna agreement is not suitable for medical education : a German view [PDF]

open access: yes, 2010
Central elements of the Bologna declaration have been implemented in a huge variety of curricula in humanities, social sciences, natural sciences and engineering sciences at German universities. Overall the results have been nothing less than disastrous.
Pfeilschifter, Josef Martin (Prof. Dr.)
core  

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