Results 91 to 100 of about 3,645,822 (281)

Spectrum of topics for world congresses and other activities of the International Society for Physical and Rehabilitation Medicine (ISPRM) : a first proposal [PDF]

, 2013
Background: One of the objectives of the International Society for Physical and Rehabilitation Medicine is to improve the continuity of World Congresses.
Fialka-Moser, Veronika, Gutenbrunner, Christoph, Guzman, Manuel, Imamura, Marta, Li, Jianan, Li, Leonard SW, Stucki, Gerold, Vanderstraeten, Guy, Ward, Anthony B   +8 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Is there progress in the adsorbent development for water treatment?

iScience
Summary: Adsorption technology is an essential part of modern water treatment. However, only a handful of adsorbent materials are used industrially, which is in striking contrast with the exponentially increasing scientific publishing activity.
Tero Luukkonen, Juhani Teeriniemi
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Climate change induced water stress and future semiconductor supply chain risk

iScience
Summary: Climate change is a driver of water stress risk globally. Semiconductor manufacturing requires large volumes of water. Existing research at the intersection of water stress risk and semiconductor manufacturing offers snapshots of current ...
Josh Lepawsky
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Engineering Sciences in Philosophical Perspective: Ontology, Epistemology, and Ethics

NanoEthics
The growth and dissemination of scientific knowledge are characteristic of contemporary engineering worldwide. In recent decades, the distinctive features of engineering sciences have been discussed in comparison to both the natural sciences and other ...
Dazhou Wang, Aleksandra Kazakova
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Drawing power from a patchwork: Harnessing a decentralized electricity grid

iScience
Summary: Much recent scholarship on the U.S. electricity system focuses on challenges from increasing demand, growing complexity, and regulatory complications.
Brent Heard, K. John Holmes
doaj   +1 more source