Results 91 to 100 of about 1,596,446 (317)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Cahiers de la Recherche sur l'Education et les Savoirs, 2017 Due to globalisation and industrial development, the Vietnamese government has seen the need to enhance engineering training in its universities to face these new challenges.
Emmanuel Cardona Gil, Denis Lemaître
doaj +1 more source
Examples of finite element mesh generation using SDRC IDEAS [PDF]
, 1990 IDEAS (Integrated Design Engineering Analysis Software) offers a comprehensive package for mechanical design engineers. Due to its multifaceted capabilities, however, it can be manipulated to serve the needs of electrical engineers, also.
Volakis, John L., Zapp, John
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Freehand Sketching for Engineers: A Pilot Study [PDF]
, 2013 This paper describes a pilot study to evaluate Freehand Sketching for Engineers, a one credit, five week course taught to undergraduate engineering students.
Goldberg, Jay R. +2 more
core +1 more source
Microbiology Spectrum, 2014 ABSTRACTAdvanced molecular biology techniques developed during the past few decades have allowed the industry to exploit and commercialize the natural defense mechanisms that antibodies provide. This review discusses the latest advances in antibody-engineering technologies to enhance clinical efficacy and outcomes.
Kin-Ming, Lo +2 more
openaire +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
The 5I Formula for Successful Staffing of Scientific and Research Organizations
Marketing of Scientific and Research Organizations, 2018 Scientists and engineers create the scientific and technological knowledge to generate societal and individual wealth and related economic growth.
Zehner William Bradley +1 more
doaj +1 more source
Experiences and issues for environmental science sensor network deployments [PDF]
, 2012 Sensor network research is a large and growing area of academic effort, examining technological and deployment issues in the area of environmental monitoring. These technologies are used by environmental engineers and scientists to monitor a multiplicity
Anda, M. +3 more
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source