Results 81 to 90 of about 124,932 (269)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
After having been mainly used in urban geography, then cast aside by the geographers, mental maps are now the object of renewed interest, particularly in the field of environmental geography.
Servane Gueben-Venière
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Putting the Engineering into Software Engineering Education [PDF]
Based on over 20 years of teaching and research experience, the author provides his assessment of software engineering education. He then builds on the analysis to provide recommendations on how we need to diverge from computer science to increase our impact, gain credibility, and ultimately ensure the success and recognition of our young discipline. A
openaire +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Engineering and reverse-engineering morality.
Recent years have witnessed a burst of progress on building formal models of moral decision-making. In psychology, neuroscience and philosophy, the goal has been to “reverse-engineer” the principles of human morality. Meanwhile, in AI ethics, the goal has been to engineer systems that can make moral decisions, in some ways inspired by how humans do ...
Levine, Sydney +3 more
openaire +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Background and Study Aim. Physical training plays a crucial role in preparing future specialists for the demands of the oil and gas industry, where physical endurance and coordination are essential for professional activities.
Roman Boichuk +6 more
doaj +1 more source
Engineers and engineering history: problems and perspectives [PDF]
In past decades, the history of engineers and engineering has seen spectacular development. Despite this, major interrogations are still left unanswered. This article examines some of these pending questions, like the type of relation that exists between engineering knowledge and practice, or the complex articulation between continuities and ...
openaire +4 more sources
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source

