Results 61 to 70 of about 5,395,832 (304)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Transactions of the American Institute of Electrical Engineers.

open access: yes, 1951
"Index of current electrical literature," Dec. 1887- appended to v. 5-Vols. for 1948-1951 published in 2 parts."Index of current electrical literature," Dec. 1887- appended to v. 5-Mode of access: Internet.Vols. 1-17, 1884-1900, 1 v.; vols.
American Institute of Electrical Engineers.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Brotherhood of Locomotive Engineers charter

open access: yes, 1884
Grand International Brotherhood of Locomotive Engineers charter, Ozark Division #83, North Springfield, Missouri. Legible names on the document include J.R. Moore, P.M.
Brotherhood of Locomotive Engineers (U.S.)
core  

Let’s do Engineering broadens young children’s understanding of engineers

open access: yesFrontiers in Education
This study developed and applied a new job card methodology to investigate what 5-year-old children in Scotland understand in relation to engineers and engineering.
Helen Bridle, Gnanathusharan Rajendran
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Transactions of the American Institute of Mining Engineers.

open access: yes, 1873
Mode of access: Internet.Vols. 1-5 in v. 5; Vols. 1-15. 1 v.; Vols. 11-25. 1 v.; Vols. 21-25. 1 v.; Vols. 1(1871)-35 (1904). 1 v.; Vols. 36 (1905)-55 (1915). 1 v.; Vols. 56 (1916)-72 (1925). 1 v.
American Institute of Mining Engineers.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The port of Cleveland, Ohio /

open access: yes, 1932
At head of title: War Department. Corps of Engineers, United States Army and United States Shipping Board.; "April 17, 1931. ... The Chief of Engineers, United States Army...."--p.
United States. Board of Engineers for Rivers and Harbors.
core  

Engineers' Forum

open access: yes, 2002
Published since 1981, Engineers' Forum is Virginia Tech's interdisciplinary student-staffed engineering magazine. It covers the latest updates and articles regarding the achievements and initiatives of the Virginia Tech engineering community and the ...
Virginia Polytechnic Institute and State University. Student Engineers' Council
core   +1 more source

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