Results 51 to 60 of about 5,395,832 (304)

Texas Board of Professional Engineers Newsletter

open access: yes, 1996
Newsletter of the Texas Board of Professional Engineers discussing information about the Board as well as news, events, legal regulations, and other relevant ...
Texas. Board of Professional Engineers.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

STEM and the creative and cultural industries: the factors keeping engineers from careers in the CCIs

open access: yesFrontiers in Communication
Engineers in the Creative and Cultural Industries (CCIs) are underrepresented, despite high demand for their expertise resulting from digitalization. Increasing the quantity of engineers in CCIs has emerged as a policy goal, since experiments have shown ...
Aliya Turegeldinova   +5 more
doaj   +1 more source

Engineering allostery [PDF]

open access: yesTrends in Genetics, 2014
Allosteric proteins have great potential in synthetic biology, but our limited understanding of the molecular underpinnings of allostery has hindered the development of designer molecules, including transcription factors with new DNA-binding or ligand-binding specificities that respond appropriately to inducers.
Raman, Srivatsan   +4 more
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The role of semiotic engineering in software engineering [PDF]

open access: yesProceedings of the 5th International Workshop on Theory-Oriented Software Engineering, 2016
Semiotic engineering is based upon the semiotic theory of Human-Computer Interaction (HCI), which focuses on communication between designers and users. Semiotic engineering tries to improve users’ interpretation through meta- communication and emphasizes that designers should play the role of legitimate interlocutors in interactive systems.
Vahdat Abdelzad   +2 more
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Spaces of interdisciplinary in/congruity: the coming together of engineers and social scientists in planning for sustainable urban environments

open access: yesInternational Journal of Urban Sustainable Development, 2020
In the context of a globalised interdisciplinary moment, where boundary-crossing research collaborations are valorised, this paper considers encounters between multidisciplinary researchers.
Sophie Hadfield-Hill   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Engineers' Forum

open access: yes, 1994
Published since 1981, Engineers' Forum is Virginia Tech's interdisciplinary student-staffed engineering magazine. It covers the latest updates and articles regarding the achievements and initiatives of the Virginia Tech engineering community and the ...
Virginia Polytechnic Institute and State University. Student Engineers' Council
core   +2 more sources

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